Department of Forensic Medicine, Inner Mongolia Medical University, Hohhot, 010059, China.
Judicial Authentication Research Institute, Liaoning University, Shenyang, 110036, China.
Curr Med Sci. 2023 Jun;43(3):609-614. doi: 10.1007/s11596-023-2735-4. Epub 2023 Apr 28.
In this study, we aimed to assess the characteristics of the P3 component from an event-related potential (ERP) that was induced by visual acuity (VA) processing. Furthermore, we sought to provide electrophysiological evidence for the objective evaluation of VA.
We recruited 32 participants with myopia-related ametropia. They reported no other ocular diseases and had an uncorrected VA of 4.0 in both eyes. We used the block letter "E" at different visual angles and orientations as the graphic stimuli. The oddball paradigm, consisting of 4 modules, was used for ERP analysis. The standard stimuli of each module were identical, with a visual angle of 1°15'. The visual angles of the target stimuli were 1°15', 55', 24', and 15'. The VA test was performed on each eye separately for all participants, and all characteristics of the P3 component were analyzed.
There was no significant difference in the P3 peak letencies between the target stimulation angle 1°15' group and the 55' group, or between the target stimulation angle 24' group and the 15' group. There was a significant difference in the P3 peak letencies between the target stimulation angle 1°15' group and the 24' group as well as the 15' group. There was a significant difference in the P3 peak letencies between the target stimulation angle 55' group and the 24' group as well as the 15' group. No significant differences were observed in the P3 amplitude between modules.
In the oddball paradigm, P3 elicitation indicated a cognitive response to the target stimuli. These data showed that the characteristics of P3 can be used as an objective evaluation of VA.
本研究旨在评估由视觉敏锐度（VA）处理诱发的事件相关电位（ERP）中的 P3 成分的特征。此外，我们旨在为 VA 的客观评估提供电生理证据。
我们招募了 32 名有近视相关屈光不正的参与者。他们报告没有其他眼部疾病，双眼未经矫正的 VA 均为 4.0。我们使用不同视角和方向的块状字母“E”作为图形刺激。使用由 4 个模块组成的Oddball 范式进行 ERP 分析。每个模块的标准刺激是相同的，视角为 1°15'。目标刺激的视角分别为 1°15'、55'、24'和 15'。所有参与者均分别对每只眼睛进行 VA 测试，并分析 P3 成分的所有特征。
目标刺激角度为 1°15'的组与 55'的组之间，以及目标刺激角度为 24'的组与 15'的组之间，P3 峰潜伏期无显著差异。目标刺激角度为 1°15'的组与 24'的组以及 15'的组之间，P3 峰潜伏期有显著差异。目标刺激角度为 55'的组与 24'的组以及 15'的组之间，P3 峰潜伏期有显著差异。模块之间 P3 振幅无显著差异。
在Oddball 范式中，P3 引发表明对目标刺激的认知反应。这些数据表明，P3 的特征可用于 VA 的客观评估。
