Noggle F T, Clark C R
J Forensic Sci. 1986 Apr;31(2):732-42.
The high-performance liquid chromatographic resolution of the enantiomers of amphetamine, methamphetamine, ephedrine, and pseudoephedrine is described. The sugar isothiocyanate, 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate (GITC), is used as a chiral derivatizing agent, with chromatographic separations of the diastereomers formed with each amine made using a standard achiral C18 stationary phase.
描述了苯丙胺、甲基苯丙胺、麻黄碱和伪麻黄碱对映体的高效液相色谱分离。糖异硫氰酸酯,2,3,4,6-四-O-乙酰基-β-D-吡喃葡萄糖基异硫氰酸酯(GITC),用作手性衍生化试剂,使用标准的非手性C18固定相分离与每种胺形成的非对映异构体。