Cappilli S, Suppa M, Ricci C, Del Marmol V, Peris K, Di Stefani A
UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche Addominali ed Endrocrino Metaboliche, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Rome, Italy.
Dermatologia, Università Cattolica del Sacro Cuore, Rome, Italy.
J Eur Acad Dermatol Venereol. 2023 Apr 28. doi: 10.1111/jdv.19149.
Cutaneous vascular lesions (VLs) are benign or malignant processes involving blood and/or lymphatic vessels, usually readily diagnosed with dermoscopy. However, cases showing unclear clinical/dermoscopic findings may require further investigations. Line-field confocal optical coherence tomography (LC-OCT) is a new, non-invasive imaging technique displaying high resolution and deep penetration. The aim of this study was to describe the LC-OCT features of the most common benign and malignant VLs and to correlate them with histopathological substrates.
Clinical, dermoscopic, LC-OCT and histopathological images of VLs were retrospectively collected. Detailed LC-OCT description and histopathological correlations were produced for different types of VLs.
The study included 71 VLs belonging to 50 caucasian patients [31 (62%) females; median age 56.8 (30-83) years] study lesions included 25 cherry haemangiomas, 15 angiokeratomas, 10 thrombosed haemangiomas, six pyogenic granulomas, five venous lakes, four targetoid haemosiderotic haemangiomas, four Kaposi's sarcomas and two extraungual glomus tumours. LC-OCT detected increased dermal vascularity, assuming different size and shape according to the particular type of VLs. LC-OCT criteria correlated well to established histopathologic findings.
The results of our preliminary observations indicate that in vivo evaluation with LC-OCT may provide practical clues for the identification of the vascular nature of a lesion and its differential diagnosis.
皮肤血管病变（VLs）是涉及血液和/或淋巴管的良性或恶性病变，通常通过皮肤镜检查很容易诊断。然而，临床/皮肤镜检查结果不明确的病例可能需要进一步检查。线场共聚焦光学相干断层扫描（LC-OCT）是一种新的非侵入性成像技术，具有高分辨率和深穿透性。本研究的目的是描述最常见的良性和恶性VLs的LC-OCT特征，并将它们与组织病理学基质相关联。
回顾性收集VLs的临床、皮肤镜、LC-OCT和组织病理学图像。针对不同类型的VLs进行了详细的LC-OCT描述和组织病理学相关性分析。
该研究纳入了来自50名白种人患者的71个VLs[31名（62%）女性；中位年龄56.8（30-83）岁]。研究病变包括25个樱桃状血管瘤、15个血管角化瘤、10个血栓性血管瘤、6个化脓性肉芽肿、5个静脉湖、4个靶样含铁血黄素性血管瘤、4个卡波西肉瘤和2个甲床外血管球瘤。LC-OCT检测到真皮血管增多，根据VLs的特定类型呈现不同的大小和形状。LC-OCT标准与既定的组织病理学结果相关性良好。
我们初步观察的结果表明，LC-OCT的体内评估可为病变血管性质的识别及其鉴别诊断提供实用线索。
