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[Studies on beta-lactam antibiotics for medicinal purpose. XIX. Synthesis and structure-activity relationships of 7 beta-acylamido-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-3-cep hem-4-carbox ylic acid, 7 beta-acylamido-3-[(5-chloro-1,2,4-triazol-1-yl)methyl]-3-c ephem-4-carb oxylic acid and their derivatives].

作者信息

Sadaki H, Imaizumi H, Inaba T, Hirakawa T, Murotani Y, Watanabe Y, Minami S, Saikawa I

出版信息

Yakugaku Zasshi. 1986 Feb;106(2):147-53.

PMID:3712239
Abstract
摘要

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1
[Studies on beta-lactam antibiotics for medicinal purpose. XIX. Synthesis and structure-activity relationships of 7 beta-acylamido-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-3-cep hem-4-carbox ylic acid, 7 beta-acylamido-3-[(5-chloro-1,2,4-triazol-1-yl)methyl]-3-c ephem-4-carb oxylic acid and their derivatives].[用于医药目的的β-内酰胺抗生素研究。十九。7β-酰基氨基-3-[(5-甲基-2H-四唑-2-基)甲基]-3-头孢烯-4-羧酸、7β-酰基氨基-3-[(5-氯-1,2,4-三唑-1-基)甲基]-3-头孢烯-4-羧酸及其衍生物的合成与构效关系]
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2
[Studies on beta-lactam antibiotics for medicinal purpose. XVIII. Synthesis and structure-activity relationships of 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3- substitut ed methyl-3-cephem-4-carboxylic acid derivatives].[用于医药目的的β-内酰胺抗生素研究。十八。7β-[(Z)-2-(2-氨基噻唑-4-基)-2-甲氧基亚氨基乙酰胺基]-3-取代甲基-3-头孢烯-4-羧酸衍生物的合成及构效关系]
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[Synthetic cephalosporins. IV. Synthesis and antibacterial activity of 7 beta-[(Z)-2-(2-aminothiazol-4-yl)-2-(O-substituted oxyimino)acetamido]-3-(1,2,3-triazol-1-yl)methyl-3-cephem-4-carboxylic acid and related compounds].[合成头孢菌素。IV. 7β-[(Z)-2-(2-氨基噻唑-4-基)-2-(O-取代氧亚氨基)乙酰胺基]-3-(1,2,3-三唑-1-基)甲基-3-头孢烯-4-羧酸及相关化合物的合成与抗菌活性]
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J Antibiot (Tokyo). 1986 Feb;39(2):215-29.