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内置端口对乳房扩张器重建后乳腺癌患者乳房切除术后放疗剂量分布的影响。

Effect of internal port on dose distribution in post-mastectomy radiotherapy for breast cancer patients after expander breast reconstruction.

作者信息

Perrucci Elisabetta, Marcantonini Marta, Arena Eleonora, Fulcheri Christian, Reggioli Valentina, Dipilato Anna Concetta, Palumbo Isabella, Saldi Simonetta, Falcinelli Lorenzo, Ingrosso Gianluca, Bini Vittorio, Aristei Cynthia

机构信息

Radiation Oncology Section, Perugia General Hospital, Perugia, Italy.

Medical Physics Unit, Perugia General Hospital, Perugia, Italy.

出版信息

Rep Pract Oncol Radiother. 2023 Apr 6;28(1):1-8. doi: 10.5603/RPOR.a2023.0014. eCollection 2023.

Abstract

BACKGROUND

In patients with expander-based reconstruction a few dosimetric analyses detected radiation therapy dose perturbation due to the internal port of an expander, potentially leading to toxicity or loss of local control. This study aimed at adding data on this field.

MATERIALS AND METHODS

A dosimetric analysis was conducted in 30 chest wall treatment planning without and with correction for port artifact. In plans with artifact correction density was overwritten as 1 g/cm. Medium, minimum and maximum chest wall doses were compared in the two plans. Both plans, with and without correction, were compared on an anthropomorphic phantom with a tissue expander on the chest covered by a simulating the skin. dosimetry was carried out on the phantom and three patients by using film strips during one treatment fraction. Estimated doses and measured film doses were compared.

RESULTS

No significant differences emerged in the minimum, medium and maximum doses in the two plans, without and with correction for port artifacts. and analyses showed a good correspondence between detected and calculated doses without and with correction.

CONCLUSIONS

The port did not significantly affect dose distribution in patients who will receive post-mastectomy radiation therapy.

摘要

背景

在采用扩张器进行乳房重建的患者中,一些剂量分析发现,扩张器的内置端口会导致放射治疗剂量扰动,这可能会导致毒性反应或局部控制丧失。本研究旨在补充该领域的数据。

材料与方法

对30例胸壁治疗计划进行了剂量分析,分别分析了未校正和校正端口伪影的情况。在进行伪影校正的计划中,密度被覆盖为1g/cm³。比较了两种计划中胸壁的平均剂量、最小剂量和最大剂量。对一个带有组织扩张器的人体模型进行了比较,该模型胸部覆盖有模拟皮肤的材料,分别比较了校正和未校正的两种计划。在一次治疗分次期间,通过使用胶片条对该模型和三名患者进行了剂量测定。比较了估计剂量和测量的胶片剂量。

结果

在未校正和校正端口伪影的两种计划中,最小剂量、平均剂量和最大剂量均未出现显著差异。γ分析表明,校正和未校正的检测剂量与计算剂量之间具有良好的一致性。

结论

端口对接受乳房切除术后放射治疗的患者的剂量分布没有显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea7/10132188/721aa9fb5460/rpor-28-1-1f1.jpg

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