Nippon Shokubai Research Alliance Laboratories, 2-1, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka, 565-0871, Japan.
Carbohydr Res. 2023 Jun;528:108812. doi: 10.1016/j.carres.2023.108812. Epub 2023 Apr 26.
Cellulose succinates (CSs) having degrees of substitution (DSs) ranging from 0.78 to 2.77 were successfully obtained by reacting cellulose with succinic anhydride (SA) in dimethyl sulfoxide at room temperature using a small amount of inexpensive solid potassium carbonate as a catalyst. Interestingly, CSs with higher DS values were obtained with a much smaller amount of catalyst than previously reported. Moreover, it is possible to control the DS by tailoring the reaction time and mass ratio of cellulose/SA. The hydroxyl groups at the C-6, C-2, and C-3 positions were the main esterification positions. In this process, most of the raw materials are either incorporated into the product or are recoverable. The E-factor, which reflects the sustainability of a given process, was demonstrated to be reduced by 93% by recovering the raw materials.
成功地在室温下以少量廉价的固体碳酸钾作为催化剂，用纤维素和琥珀酸酐（SA）在二甲基亚砜中反应，得到取代度（DS）在 0.78 至 2.77 之间的纤维素琥珀酸酯（CSs）。有趣的是，与之前报道的相比，使用更少的催化剂即可获得具有更高 DS 值的 CSs。此外，通过调整反应时间和纤维素/SA 的质量比，可以控制 DS。C-6、C-2 和 C-3 位的羟基是主要的酯化位置。在这个过程中，大部分原料要么被纳入产物中，要么是可回收的。通过回收原料，所展示的 E 因子（反映给定过程可持续性的指标）降低了 93%。
