Chew Zi Hao, Lim Eng Haw, Sairin Mohd Eksan, Wan Hamizan Aneeza Khairiyah
Department of Otorhinolaryngology Head & Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.
Department of Otolaryngology - Head and Neck Surgery, Hospital Miri, Miri, MYS.
Cureus. 2023 Mar 30;15(3):e36901. doi: 10.7759/cureus.36901. eCollection 2023 Mar.
Solitary fibrous tumors of the nasal cavity and paranasal sinuses are rarely encountered in clinical practice. These are unusual mesenchymal tumours initially described as primary spindle-cell neoplasms. Such tumours may manifest in pleural and extrapleural sites such as the liver, parapharyngeal space, sublingual and parotid glands, and thyroid but are seldom described in the nose and paranasal sinus region. Erosion of adjacent structures may occur, but the tumour itself does not metastasise. A young patient presented with a progressive unilateral nasal mass. The initial nasal biopsy reported it as a benign inflammatory nasal polyp. Imaging revealed a large, locally expansile mass within the right nasal cavity displacing the nasal septum. The patient underwent excision of the tumour and the diagnosis of solitary fibrous tumour was confirmed by immunohistochemistry staining. This case is intended to highlight the diagnosis and management of this rare tumour.
鼻腔和鼻窦的孤立性纤维瘤在临床实践中很少见。这些是不寻常的间叶性肿瘤,最初被描述为原发性梭形细胞瘤。此类肿瘤可出现在胸膜和胸膜外部位,如肝脏、咽旁间隙、舌下腺和腮腺以及甲状腺,但在鼻和鼻窦区域很少有描述。可能会发生相邻结构的侵蚀,但肿瘤本身不会转移。一名年轻患者出现进行性单侧鼻腔肿物。最初的鼻腔活检报告为良性炎性鼻息肉。影像学检查显示右侧鼻腔内有一个大的、局部膨胀性肿物,使鼻中隔移位。患者接受了肿瘤切除,免疫组织化学染色证实为孤立性纤维瘤。本病例旨在强调这种罕见肿瘤的诊断和管理。