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可卡因使用和甲状腺毒症危象引发的儿茶酚胺大风暴

Catecholamine Mega Storm Triggered by Cocaine Use and Thyrotoxicosis Crisis.

作者信息

Oredegbe Al Ameen, Awad Mina

机构信息

Internal Medicine, Albany Medical Center, Albany, USA.

出版信息

Cureus. 2023 Apr 29;15(4):e38299. doi: 10.7759/cureus.38299. eCollection 2023 Apr.

DOI:10.7759/cureus.38299
PMID:37128599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10148666/
Abstract

Takotsubo cardiomyopathy (TCM) is a well-recognized non-ischemic complication of physical and emotional stressors leading to heart dysfunction. Both thyroid storm and cocaine have been implicated with TCM to varying degrees. We present the case of a 26-year-old male with Graves' disease and cocaine abuse who was hospitalized with thyroid storm resulting in takotsubo cardiomyopathy and cardiogenic shock. The patient had a long and complicated hospital course, requiring advanced therapies including extracorporeal membrane oxygenation and other medical and mechanical circulatory support therapies. With treatment for thyroid storm using antithyroid medications and steroids, the patient eventually had complete recovery of his left ventricular function and was ultimately weaned from pressors, inotropes and mechanical support.

摘要

应激性心肌病(TCM)是一种公认的由身体和情绪应激源导致心脏功能障碍的非缺血性并发症。甲状腺风暴和可卡因都在不同程度上与应激性心肌病有关。我们报告一例26岁患有格雷夫斯病且滥用可卡因的男性患者,该患者因甲状腺风暴住院,导致应激性心肌病和心源性休克。患者有漫长而复杂的住院过程,需要包括体外膜肺氧合在内的高级治疗以及其他药物和机械循环支持治疗。通过使用抗甲状腺药物和类固醇治疗甲状腺风暴,患者最终左心室功能完全恢复,并最终停用升压药、强心药和机械支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/e4a234bbdf20/cureus-0015-00000038299-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/cab789c8ef5e/cureus-0015-00000038299-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/c77273e1daf8/cureus-0015-00000038299-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/b8867f79bfe2/cureus-0015-00000038299-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/e4a234bbdf20/cureus-0015-00000038299-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/cab789c8ef5e/cureus-0015-00000038299-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/c77273e1daf8/cureus-0015-00000038299-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/b8867f79bfe2/cureus-0015-00000038299-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2228/10148666/e4a234bbdf20/cureus-0015-00000038299-i04.jpg

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本文引用的文献

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Takotsubo Cardiomyopathy After Cocaine Intoxication.可卡因中毒后应激性心肌病
Eur J Case Rep Intern Med. 2022 Sep 2;9(9):003457. doi: 10.12890/2022_003457. eCollection 2022.
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Thyroid Storm-induced Takotsubo Cardiomyopathy Presenting as Acute Chest Pain: A Case Report.以急性胸痛为表现的甲状腺风暴诱发的应激性心肌病:一例报告
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Management of Cardiogenic Shock due to Thyrotoxicosis: A Systematic Literature Review.甲状腺毒症性心原性休克的治疗:系统文献回顾。
以心脏骤停为首发表现的可卡因诱发的应激性心肌病:一例报告及文献复习
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