Institut für AudioNeuroTechnologie (VIANNA) & Abt. für experimentelle Otologie, Exzellenzcluster Hearing4All, Medizinische Hochschule Hannover (Abteilungsleiter und Institutsleiter: Prof. Dr. A. Kral) & Australian Hearing Hub, School of Medicine and Health Sciences, Macquarie University, Sydney, Australia.
Laryngorhinootologie. 2023 May;102(S 01):S3-S11. doi: 10.1055/a-1973-5087. Epub 2023 May 2.
The human brain shows extensive development of the cerebral cortex after birth. This is extensively altered by the absence of auditory input: the development of cortical synapses in the auditory system is delayed and their degradation is increased. Recent work shows that the synapses responsible for corticocortical processing of stimuli and their embedding into multisensory interactions and cognition are particularly affected. Since the brain is heavily reciprocally interconnected, inborn deafness manifests not only in deficits in auditory processing, but also in cognitive (non-auditory) functions that are affected differently between individuals. It requires individualized approaches in therapy of deafness in childhood.
人类大脑在出生后表现出广泛的大脑皮层发育。这种发育会因听觉输入的缺失而受到广泛影响:听觉系统中皮质突触的发育会延迟,其退化速度会加快。最近的研究表明,负责刺激的皮质间处理以及将其嵌入多感觉相互作用和认知的突触受到了特别的影响。由于大脑是高度相互关联的,先天性耳聋不仅表现为听觉处理缺陷,还表现为受个体差异影响的认知(非听觉)功能障碍。这就需要在儿童期耳聋的治疗中采用个体化的方法。