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脊柱麻醉与全身麻醉在髋部骨折手术中效果的改善:国家手术质量改进计划的回顾性队列研究。

Improved outcomes for spinal versus general anesthesia for hip fracture surgery: a retrospective cohort study of the National Surgical Quality Improvement Program.

机构信息

Department of Anesthesiology, NewYork-Presbyterian Weill Cornell Medical Center, New York, New York, USA.

Department of Anesthesiology, NewYork-Presbyterian Weill Cornell Medical Center, New York, New York, USA

出版信息

Reg Anesth Pain Med. 2024 Jan 11;49(1):4-9. doi: 10.1136/rapm-2022-104217.

Abstract

BACKGROUND

There is a lack of consensus in the literature as to whether anesthetic modality influences perioperative complications in hip fracture surgery. The aim of the present study was to assess the effect of spinal anesthesia compared with general anesthesia on postoperative morbidity and mortality in patients who underwent hip fracture surgery using data from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP).

METHODS

We used the ACS NSQIP to identify patients aged 50 and older who received either spinal or general anesthesia for hip fracture surgery from 2016 to 2019. Propensity-score matching was performed to control for clinically relevant covariates. The primary outcome of interest was the combined incidence of stroke, myocardial infarction (MI) or death within 30 days. Secondary outcomes included 30-day mortality, hospital length of stay and operative time.

RESULTS

Among the 40 527 patients aged 50 and over who received either spinal or general anesthesia for hip fracture surgery from 2016 to 2019, 7358 spinal anesthesia cases were matched to general anesthesia cases. General anesthesia was associated with a higher incidence of combined 30-day stroke, MI or death compared with spinal anesthesia (OR 1.219 (95% CI 1.076 to 1.381); p=0.002). General anesthesia was also associated with a higher frequency of 30-day mortality (OR 1.276 (95% CI 1.099 to 1.481); p=0.001) and longer operative time (64.73 vs 60.28 min; p<0.001). Spinal anesthesia had a longer average hospital length of stay (6.29 vs 5.73 days; p=0.001).

CONCLUSION

Our propensity-matched analysis suggests that spinal anesthesia as compared with general anesthesia is associated with lower postoperative morbidity and mortality in patients undergoing hip fracture surgery.

摘要

背景

文献中对于麻醉方式是否会影响髋部骨折手术的围手术期并发症尚无共识。本研究旨在使用美国外科医师学会国家手术质量改进计划(ACS NSQIP)的数据评估椎管内麻醉与全身麻醉对接受髋部骨折手术患者术后发病率和死亡率的影响。

方法

我们使用 ACS NSQIP 从 2016 年至 2019 年确定了 50 岁及以上接受椎管内或全身麻醉行髋部骨折手术的患者。采用倾向评分匹配法控制临床相关协变量。主要观察指标为 30 天内卒中、心肌梗死(MI)或死亡的联合发生率。次要结局包括 30 天死亡率、住院时间和手术时间。

结果

在 2016 年至 2019 年期间接受椎管内或全身麻醉行髋部骨折手术的 40527 名 50 岁及以上患者中,7358 例椎管内麻醉病例与全身麻醉病例匹配。与椎管内麻醉相比,全身麻醉与 30 天内联合卒中、MI 或死亡的发生率较高(比值比 1.219(95%可信区间 1.076 至 1.381);p=0.002)。全身麻醉还与 30 天死亡率较高相关(比值比 1.276(95%可信区间 1.099 至 1.481);p=0.001)和手术时间较长(64.73 分钟比 60.28 分钟;p<0.001)。椎管内麻醉的平均住院时间较长(6.29 天比 5.73 天;p=0.001)。

结论

我们的倾向性匹配分析表明,与全身麻醉相比,椎管内麻醉与接受髋部骨折手术患者的术后发病率和死亡率较低相关。

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