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[Cyclosporin treatment in uveitis].

作者信息

Quentin C D, Vogel M

出版信息

Klin Monbl Augenheilkd. 1986 Mar;188(3):248-50. doi: 10.1055/s-2008-1050623.

DOI:10.1055/s-2008-1050623
PMID:3713099
Abstract

With Cyclosporin, a recently developed immunosuppressant drug, the authors treated eight patients with noninfectious chronic uveitis: intermediate uveitis (4), Behcet's disease (2), chorioiditis (1), and anterior uveitis (1). Therapy had to be discontinued in six patients who responded poorly or manifested severe side effects. In four cases the Cyclosporin concentration in the aqueous humor was determined. In spite of a concentration of about 900 ng/ml there was a deterioration in two cases with intermediate uveitis and Behcet's disease. Only one of the eight patients with intermediate uveitis responded well without any recurrence.

摘要

相似文献

1
[Cyclosporin treatment in uveitis].
Klin Monbl Augenheilkd. 1986 Mar;188(3):248-50. doi: 10.1055/s-2008-1050623.
2
Cyclosporin A in the treatment of posterior uveitis.
Trans Ophthalmol Soc U K (1962). 1985;104 ( Pt 2):146-51.
3
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引用本文的文献

1
Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders.环孢素。对其药效学和药代动力学特性以及在免疫调节紊乱中的治疗应用的综述。
Drugs. 1993 Jun;45(6):953-1040. doi: 10.2165/00003495-199345060-00007.
2
Cyclosporin in the treatment of severe chronic idiopathic uveitis.环孢素治疗重度慢性特发性葡萄膜炎。
Br J Ophthalmol. 1990 Jun;74(6):344-9. doi: 10.1136/bjo.74.6.344.