Pommer W, Krause P H, Berg P A, Neumayer H H, Mihatsch M J, Molzahn M
Klin Wochenschr. 1986 Mar 17;64(6):290-3. doi: 10.1007/BF01711941.
A case of acute interstitial nephritis (AIN) developing after cefaclor treatment is reported. Diagnosis was proofed by kidney biopsy and lymphocyte transformation test. The clinical course of the patient with non-oliguric renal failure was favourable. Four weeks after discontinuation of cefaclor treatment the renal function was completely restored and remained stable over the ten-month follow-up period. It is concluded that cefaclor can cause hyperallergic AIN and acute renal failure.
报告了1例头孢克洛治疗后发生急性间质性肾炎（AIN）的病例。通过肾活检和淋巴细胞转化试验确诊。该非少尿型肾衰竭患者的临床病程良好。停用头孢克洛治疗4周后，肾功能完全恢复，在10个月的随访期内保持稳定。结论是头孢克洛可引起超敏性AIN和急性肾衰竭。
