Bøg Martin, Filges Trine, Jørgensen Anne Marie Klint
Campbell Syst Rev. 2018 Jun 1;14(1):1-127. doi: 10.4073/csr.2018.6. eCollection 2018.
This Campbell systematic review examines the effects of deployment on mental health. The review summarizes evidence from 185 studies. All studies used observational data to quantify the effect of deployment. This review includes studies that evaluate the effects of deployment on mental health. A total of 185 studies were identified. However, only 40 of these were assessed to be of sufficient methodological quality to be included in the final analysis. The studies spanned the period from 1993 to 2017 and were mostly carried out in the USA, UK and Australia. The studies all had some important methodological weaknesses. None of the included studies used experimental designs (random assignment). Deployment to military operations negatively affects the mental health functioning of deployed military personnel. For assessments taken more than 24 months since exposure, we consistently found adverse effects of deployment on all mental health domains (PTSD, depression, substance abuse/dependence, and common mental disorders), particularly on PTSD. For assessments taken less than 24 months (or a variable number of months since exposure) the evidence was less consistent and in many instances inconclusive.
While additional research is needed, the current evidence strongly supports the notion that deployment negatively affects mental health functioning of deployed military personnel. When military personnel are deployed to military operations abroad they face an increased risk of physical harm, and an increased risk of adverse shocks to their mental health.The primary condition under consideration is deployment to an international military operation. Deployment to a military operation is not a uniform condition; rather, it covers a range of scenarios. Military deployment is defined as performing military service in an operation at a location outside the home country for a limited time period, pursuant to orders.The review included studies that reported outcomes for individuals who had been deployed. This review looked at the effect of deployment on mental health outcomes. The mental health outcomes are: post-traumatic stress disorder (PTSD), major depressive disorder (MDD), common mental disorders (depression, anxiety and somatisation disorders) and substance-related disorders.By identifying the major effects of deployment on mental health and quantifying these effects, the review can inform policy development on deployment and military activity as well as post-deployment support for veterans. In this way the review enables decision-makers to prioritise key areas. This review includes studies that evaluate the effects of deployment on mental health. A total of 185 studies were identified. However, only 40 of these were assessed to be of sufficient methodological quality to be included in the final analysis. The studies spanned the period from 1993 to 2017 and were mostly carried out in the USA, UK and Australia. The studies all had some important methodological weaknesses. None of the included studies used experimental designs (random assignment). Deployment to military operations negatively affects the mental health functioning of deployed military personnel. For assessments taken more than 24 months since exposure, we consistently found adverse effects of deployment on all mental health domains (PTSD, depression, substance abuse/dependence, and common mental disorders), particularly on PTSD. For assessments taken less than 24 months (or a variable number of months since exposure) the evidence was less consistent and in many instances inconclusive. The odds of screening positive for PTSD and depression were consistently high in the longer term. This suggests that efforts should be increased to detect and treat mental disorders, as effects may be long-lasting.Overall the risk of bias in the majority of included studies was high. While it is difficult to imagine a randomised study design to understand how deployment affects mental health, other matters such as changes to personnel policy, or unanticipated shocks to the demand for military personnel, could potentially be a rich source of quasi-experimental variation. The review authors searched for studies up to 2017. This Campbell systematic review was published in March 2018.
When military personnel are deployed to military operations abroad they face an increased risk of physical harm, and an increased risk of adverse shocks to their mental health. Research suggests that the increased risk to mental health is mainly due to the hazards of war, combat exposure: firing weapons, road side bombs, seeing fellow soldiers, friends, civilians, and enemies being injured, maimed or killed. These experiences may lead to severe mental stress. The adverse impact on mental health is the psychological cost of war, and it is of interest to policymakers to learn the magnitude of these effects. This review sets out to synthesise available evidence about the consequences of deployment for deployed military personnel in the mental health and social functioning domains. The objective of this review isto synthesise the consequences of deployment to military operation on the mental health and social functioning of deployed military personnel. We searched electronic databases, grey literature, and references from primary studies and related reviews. No language or date restrictions were applied to the searches. We searched the following electronic databases: Academic Search Elite, Cochrane Library, EMBASE, ERIC, MEDLINE, PsycINFO, Science Citation Index, Social Science Citation Index, SocINDEX, as well as the Nordic platforms: bibliotek.dk, BIBSYS, and LIBRIS. The conclusions of this review are based on the most recent searches performed. The last search was performed in April 2017. Primary studies had to meet the following inclusion criteria: Participants: The participants should be military personnel.Intervention: The condition should be deployment to a military operation.Comparison: The relevant comparisons were either comparing a) deployed military personnel to non-deployed military personnel, b) deployed military personnel to military personnel deployed elsewhere, for example personnel deployed to non-combat operations, c) military personnel deployed to the same operation but stratified by combat exposure.Outcomes: The study should report on one or more mental health outcomes, and/or social functioning for the deployed participants. In particular studies should report on one or more of the following mental health outcomes: PTSD, major depression, substance abuse or dependence (including alcohol), and common mental disorders (depression and anxiety disorders). The following social functioning outcomes were relevant: employment, and homelessness.Study Designs: Both experimental and quasi-experimental designs with a comparison group were eligible for inclusion in the review. Studies were excluded if they: Reported on deployments taking place before 1989.Used a within group pre-post study design.Did not report on at least one of the mental health or social functioning outcomes. The total number of potentially relevant studies constituted31,049records. A total of 185 studies met the inclusion criteria and were critically appraised by the review authors. The final selection of 185 studies was from 13 different countries.Forty eight of the 185 studies did not report effect estimates or provide data that would allow the calculation of an effect size and standard error. Fifty four studies were excluded because of overlapping samples. The majority of those studies were from USA but the main reason for not using studies from USA in the synthesis was lack of information to calculate an effect size. Nearly half the studies from the UK could not be used in the synthesis due to overlap of data samples. Forty three studies were judged to have a very high risk of bias (5 on the scale) and, in accordance with the protocol, we excluded these from the data synthesis on the basis that they would be more likely to mislead than inform., Thus a total of 40 studies, from five different countries, were included in the data synthesis.Random effects models were used to pool data across the studies. We used the odds ratio. Pooled estimates were weighted with inverse variance methods, and 95% confidence intervals were calculated. The meta-analyses were carried out by time since exposure (short, medium, long, and other time since exposure) and by type of comparison (deployed versus non-deployed, all deployed but stratified by either combat operations versus non-combat operations, or stratified by combat exposure). We performed single factor subgroup analysis. The assessment of any difference between subgroups was based on 95% confidence intervals. Funnel plots were used to assess the possibility of publication bias. Sensitivity analysis was used to evaluate whether the pooled effect sizes were robust across components of methodological quality. The findings were mixed, depending on the outcome, the time since exposure and the approach (deployed versus non-deployed termed absolute or stratified by extent of combat termed relative) used to investigate the effect. It was not possible to analyse the outcomes homelessness and employment. All studies that could be used in the data synthesis reported on the impact of deployment on mental health; PTSD, depression, substance use or common mental disorder.For assessments taken less than 24 months since exposure the evidence was inconclusive either because too few studies reported results in the short and medium term and/or the degree of heterogeneity between studies was large.For assessments taken at other time points (a variable number of months since exposure) the evidence was inconclusive for the relative comparisons due to either too few studies or a substantial degree of heterogeneity between studies. For the absolute comparison the analysis of common mental disorder was inconclusive, whereas the average effects of PTSD and depression were positive and statistically significant (PTSD odds ratio (OR) was 1.91 (95% confidence interval (CI): 1.28 to 2.85) and OR=1.98 (95% CI: 1.05 to 3.70) for depression). The analysis concerning substance use indicated that deployed participants did not have higher odds of screening positive for substance use compared to non-deployed participants (OR=1.15 (95% CI: 0.98 to 1.36)).For assessments taken more than 24 months post exposure, meta-analyses indicated that the odds of screening positive for PTSD, depression, substance use and common mental disorder were higher for participants in the deployed group compared to participants in the group that were not deployed (PTSD OR=3.31 (95% CI: 2.69 to 4.07), OR=2.19 (95% CI: 1.58 to 3.03) for depression, OR=1.27 (95% CI: 1.15 to 1.39) for substance use, and OR=1.64 (95% CI: 1.38 to 1.96) for common mental disorder). Likewise, participants reporting high combat exposure had higher odds of screening positive for PTSD and depression than participants reporting lower exposure for long term assessments (PTSD OR=3.05 (95% CI: 1.94 to 4.80) and OR=1.81 (95% CI: 1.28 to 2.56) for depression). The analyses of substance use and common mental disorder were inconclusive due to too few studies.On the basis of the prevalence of mental health problems in pre-deployed or non-deployed population based comparison sampleswe would therefore expect the long term prevalence of PTSD in post-deployed samples to be in the range 6.1 - 14.9%, the long term prevalence of depression to be in the range from 7.6% to 18%, the long term prevalence of substance use to be in the range from 2.4% to 17.5% and the prevalence of common mental disorder to be in the range from 10% to 23%.Sensitivity analyses resulted in no appreciable change in effect size, suggesting that the results are robust.It was only possible to assess the impact of two types of personnel characteristics (branch of service and duty/enlistment status) on the mental health outcomes. We found no evidence to suggest that the effect of deployment on any outcomes differ between these two types of personnel characteristics. Deployment to military operations negatively affects the mental health functioning of deployed military personnel. We focused on the effect of deployment on PTSD (post-traumatic stress disorder), depression, substance abuse/dependence, and common mental disorders (depression and anxiety disorders). For assessments taken less than 24 months (or a variable number of months since exposure) the evidence was less consistent and in many instances inconclusive. For assessments taken more than 24 months since exposure, we consistently found adverse effects of deployment on all domains, particularly on PTSD. There is increased political awareness of the need to address post deployment mental health problems. The odds of screening positive for PTSD and depression were consistently high in the longer term. This suggests that efforts should be increased to detect and treat mental disorders, as effects may be long lasting. Mental illness is of particular concern in the military for operational reasons, but they may be hard to detect in the military setting because a military career is intimately linked with mental and physical strength.It was not possible to examine a number of factors which we had reason to expect would impact on the magnitude of the effect. This would have been particularly relevant from a policy perspective because these are direct parameters that one could use to optimally "organize" deployment in order to minimize impacts on mental health functioning.While additional research is needed, the current evidence strongly supports the notion that deployment negatively affects mental health functioning of deployed military personnel. The next step is to begin to examine preventive measures and policies for organizing deployment, in order to minimize the effects on mental health.
本坎贝尔系统评价考察了部署对心理健康的影响。该评价总结了185项研究的证据。所有研究均使用观察性数据来量化部署的影响。本评价纳入了评估部署对心理健康影响的研究。共识别出185项研究。然而,其中只有40项被评估为方法学质量足够高,可纳入最终分析。这些研究涵盖了1993年至2017年的时间段,大多在美国、英国和澳大利亚开展。这些研究都存在一些重要的方法学缺陷。纳入的研究均未采用实验设计(随机分配)。部署到军事行动会对被部署军事人员的心理健康功能产生负面影响。对于暴露后超过24个月进行的评估,我们始终发现部署对所有心理健康领域(创伤后应激障碍、抑郁症、物质滥用/依赖和常见精神障碍)均有不利影响,尤其是对创伤后应激障碍。对于暴露后少于24个月(或暴露后不同时长)进行的评估,证据不太一致,在许多情况下尚无定论。
虽然还需要更多研究,但目前的证据有力地支持了这样一种观点,即部署会对被部署军事人员的心理健康功能产生负面影响。当军事人员被部署到国外军事行动时,他们面临身体伤害风险增加,以及心理健康受到不利冲击的风险增加。所考虑的主要情况是部署到国际军事行动。部署到军事行动并非一种统一的情况;相反,它涵盖了一系列场景。军事部署被定义为根据命令在本国境外的一个行动中服役一段有限时间。该评价纳入了报告被部署人员结果的研究。本评价考察了部署对心理健康结果的影响。心理健康结果包括:创伤后应激障碍(PTSD)、重度抑郁症(MDD)、常见精神障碍(抑郁症、焦虑症和躯体化障碍)以及物质相关障碍。通过确定部署对心理健康的主要影响并对这些影响进行量化,该评价可为有关部署和军事活动的政策制定以及退伍军人的部署后支持提供参考。通过这种方式,该评价使决策者能够确定关键领域的优先次序。本评价纳入了评估部署对心理健康影响的研究。共识别出185项研究。然而,其中只有40项被评估为方法学质量足够高,可纳入最终分析。这些研究涵盖了1993年至2017年的时间段,大多在美国、英国和澳大利亚开展。这些研究都存在一些重要的方法学缺陷。纳入的研究均未采用实验设计(随机分配)。部署到军事行动会对被部署军事人员的心理健康功能产生负面影响。对于暴露后超过24个月进行的评估,我们始终发现部署对所有心理健康领域(创伤后应激障碍、抑郁症、物质滥用/依赖和常见精神障碍)均有不利影响,尤其是对创伤后应激障碍。对于暴露后少于24个月(或暴露后不同时长)进行的评估,证据不太一致,在许多情况下尚无定论。从长远来看,PTSD和抑郁症筛查呈阳性的几率一直很高。这表明应加大力度检测和治疗精神障碍,因为影响可能是长期的。总体而言,大多数纳入研究的偏倚风险较高。虽然很难想象采用随机研究设计来了解部署如何影响心理健康,但其他事项,如人事政策的变化或对军事人员需求的意外冲击,可能潜在地成为丰富的准实验变异来源。评价作者检索了截至2017年的研究。本坎贝尔系统评价于2018年3月发表。
当军事人员被部署到国外军事行动时,他们面临身体伤害风险增加,以及心理健康受到不利冲击的风险增加。研究表明,心理健康风险增加主要是由于战争的危害、战斗暴露:开枪射击、路边炸弹、目睹战友、朋友、平民和敌人受伤、致残或死亡。这些经历可能导致严重的精神压力。对心理健康产生不利影响是战争的心理代价,政策制定者有兴趣了解这些影响的程度。本评价旨在综合现有证据,说明部署对被部署军事人员心理健康和社会功能领域的后果。本评价的目的是综合部署到军事行动对被部署军事人员心理健康和社会功能的后果。我们检索了电子数据库、灰色文献以及原始研究和相关评价的参考文献。检索未设语言或日期限制。我们检索了以下电子数据库:学术搜索精英版、考科蓝图书馆、EMBASE、教育资源信息中心、医学期刊数据库、心理学文摘数据库、科学引文索引、社会科学引文索引、社会索引,以及北欧平台:bibliotek.dk、BIBSYS和LIBRIS。本评价的结论基于最近进行的检索。最后一次检索于2017年4月进行。原始研究必须符合以下纳入标准:参与者:参与者应为军事人员。干预措施:条件应为部署到军事行动。对照:相关对照为:a)将被部署军事人员与未被部署军事人员进行比较;b)将被部署军事人员与部署到其他地方的军事人员进行比较,例如部署到非战斗行动的人员;c)部署到同一行动但按战斗暴露分层的军事人员。结果:研究应报告被部署参与者的一项或多项心理健康结果和/或社会功能。特别是研究应报告以下一项或多项心理健康结果:创伤后应激障碍、重度抑郁症、物质滥用或依赖(包括酒精)以及常见精神障碍(抑郁症和焦虑症)。以下社会功能结果也相关:就业和无家可归。研究设计:具有对照组的实验性和准实验性设计均符合纳入本评价的条件。如果研究:报告1989年以前发生的部署;采用组内前后研究设计;未报告至少一项心理健康或社会功能结果,则予以排除。潜在相关研究总数为31,049条记录。共有185项研究符合纳入标准,并由评价作者进行了严格评估。最终选定的185项研究来自13个不同国家。185项研究中有48项未报告效应估计值或提供可计算效应大小和标准误差的数据。54项研究因样本重叠而被排除。这些研究大多来自美国,但在综合分析中未使用美国研究的主要原因是缺乏计算效应大小的信息。由于数据样本重叠,英国近一半的研究无法用于综合分析。43项研究被判定存在非常高的偏倚风险(5级),根据方案,我们将这些研究排除在数据综合分析之外,因为它们更有可能产生误导而非提供信息。因此,共有40项来自五个不同国家的研究被纳入数据综合分析。采用随机效应模型对各项研究的数据进行汇总。我们使用优势比。汇总估计值采用逆方差法加权,并计算95%置信区间。荟萃分析按暴露后的时间(短期、中期、长期以及暴露后的其他时间)和比较类型(部署组与未部署组、所有部署人员但按战斗行动与非战斗行动分层或按战斗暴露分层)进行。我们进行了单因素亚组分析。亚组间任何差异的评估基于95%置信区间。使用漏斗图评估发表偏倚的可能性。敏感性分析用于评估汇总效应大小在方法学质量各组成部分中是否稳健。根据结果、暴露后的时间以及用于研究效应评估的方法(部署组与未部署组的绝对比较或按战斗程度分层的相对比较),研究结果不一。无法分析无家可归和就业结果。所有可用于数据综合分析的研究均报告了部署对心理健康的影响:创伤后应激障碍、抑郁症、物质使用或常见精神障碍。对于暴露后少于24个月进行的评估,证据尚无定论,原因要么是在短期和中期报告结果的研究太少,要么是研究之间的异质性程度太大。对于在其他时间点(暴露后不同时长)进行的评估,由于研究太少或研究之间存在很大异质性,相对比较的证据尚无定论。对于绝对比较,常见精神障碍的分析尚无定论,而创伤后应激障碍和抑郁症的平均效应为阳性且具有统计学意义(创伤后应激障碍优势比(OR)为1.91(95%置信区间(CI):1.28至2.85),抑郁症OR = 1.98(95% CI:1.05至3.70))。关于物质使用的分析表明,与未部署参与者相比,部署参与者物质使用筛查呈阳性的几率并不更高(OR = 1.15(95% CI:0.98至1.36))。对于暴露后超过24个月进行的评估,荟萃分析表明,与未部署组的参与者相比,部署组参与者创伤后应激障碍、抑郁症、物质使用和常见精神障碍筛查呈阳性的几率更高(创伤后应激障碍OR = 3.31(95% CI:2.69至4.07),抑郁症OR = 2.19(95% CI:1.58至3.03),物质使用OR = <