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[真性红细胞增多症中用铟-111 柠檬酸盐进行骨髓闪烁显像]

[Scintigraphy of the bone marrow with 111In-citrin in polycythemia vera].

作者信息

Prikhod'ko A G, Sheptun A N, Vikman Ia E, Sorokin I N, Rozdil'skiĭ S I

出版信息

Med Radiol (Mosk). 1986 May;31(5):30-3.

PMID:3713467
Abstract

Scintigraphy of the bone marrow with 111In-citrin was performed in 32 patients with polycythemia vera and 8 controls. The method ensured an objective assessment of bone marrow function in patients with polycythemia vera. A characteristic RP scintigraphic picture corresponded to different clinical stages of the disease. A degree of a decrease in the blood radioactivity within 24 h after i. v. administration of 111In-citrin reflected the summary erythropoietic activity of the bone marrow and could serve as a differential diagnostic criterion in determining a stage of polycythemia vera.

摘要

对32例真性红细胞增多症患者和8名对照者进行了用铟-111标记的柠檬酸盐骨髓闪烁扫描。该方法确保了对真性红细胞增多症患者骨髓功能的客观评估。特征性的放射性核素闪烁扫描图像与该疾病的不同临床阶段相对应。静脉注射铟-111标记的柠檬酸盐后24小时内血液放射性的降低程度反映了骨髓的总红细胞生成活性,可作为确定真性红细胞增多症阶段的鉴别诊断标准。

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