• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Genotoxicity of gamma-irradiation in L5178Y mouse lymphoma cells.

作者信息

Moore M M, Amtower A, Strauss G H, Doerr C

出版信息

Mutat Res. 1986 Jun;174(2):149-54. doi: 10.1016/0165-7992(86)90107-7.

DOI:10.1016/0165-7992(86)90107-7
PMID:3713733
Abstract

The ability of gamma-irradiation to induce gene mutation at the thymidine kinase locus and gross chromosome aberrations in L5178Y TK+/- 3.7.2C mouse lymphoma cells was evaluated. Positive results were obtained for both end-points. The majority of mutants were found to be small-colony mutants which correlated with the induction of gross chromosome aberrations.

摘要

相似文献

1
Genotoxicity of gamma-irradiation in L5178Y mouse lymphoma cells.
Mutat Res. 1986 Jun;174(2):149-54. doi: 10.1016/0165-7992(86)90107-7.
2
The cytotoxic and mutagenic effects of UVA radiation on L5178Y mouse lymphoma cells.
Photochem Photobiol. 1986 Jul;44(1):53-7. doi: 10.1111/j.1751-1097.1986.tb03563.x.
3
Mutagenicity and clastogenicity of teniposide (VM-26) in L5178Y/TK +/- -3.7.2C mouse lymphoma cells.替尼泊苷（VM - 26）在L5178Y/TK+/- -3.7.2C小鼠淋巴瘤细胞中的致突变性和染色体断裂活性。
Mutat Res. 1987 Mar;187(3):141-9. doi: 10.1016/0165-1218(87)90081-4.
4
Comparison of chromosome aberration frequency and small-colony TK-deficient mutant frequency in L5178Y/TK(+/-)-3.7.2C mouse lymphoma cells.L5178Y/TK(+/-)-3.7.2C小鼠淋巴瘤细胞中染色体畸变频率与小集落TK缺陷型突变频率的比较
Mutagenesis. 1990 Nov;5(6):609-14. doi: 10.1093/mutage/5.6.609.
5
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.利用微核、染色体畸变和小集落TK突变体分析来定量L5178Y小鼠淋巴瘤细胞中的染色体损伤。
Mutat Res. 1989 Mar;222(3):191-203. doi: 10.1016/0165-1218(89)90135-3.
6
Mutagenicity and clastogenicity of proflavin in L5178Y/TK +/- -3.7.2.C cells.原黄素在L5178Y/TK+/- -3.7.2.C细胞中的致突变性和染色体断裂作用。
Mutat Res. 1988 Feb;204(2):323-8. doi: 10.1016/0165-1218(88)90106-1.
7
High-resolution cytogenetic analysis of L5178Y TK+/- 3.7.2C cells: variation in chromosome 11 breakpoints among small-colony TK-/- mutants.L5178Y TK+/- 3.7.2C细胞的高分辨率细胞遗传学分析：小菌落TK-/-突变体中11号染色体断点的变异
Mutat Res. 1989 Oct;214(2):195-9. doi: 10.1016/0027-5107(89)90163-2.
8
Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures.大小不同的L5178Y小鼠淋巴瘤细胞集落的染色体分析：诱变处理和对照培养物中三氟胸苷抗性和未筛选细胞集落的比较
Mutat Res. 1989 Oct;224(2):197-208. doi: 10.1016/0165-1218(89)90156-0.
9
Cytogenetic analysis of the L5178Y/TK+/- leads to TK-/- mouse lymphoma mutagenesis assay system.L5178Y/TK+/- 的细胞遗传学分析导致了TK-/- 小鼠淋巴瘤诱变检测系统的产生。
Mutat Res. 1981 Nov;84(1):169-81. doi: 10.1016/0027-5107(81)90060-9.
10
Loss of P53 heterozygosity is not responsible for the small colony thymidine kinase mutant phenotype in L5178Y mouse lymphoma cells.P53杂合性缺失与L5178Y小鼠淋巴瘤细胞中的小集落胸苷激酶突变体表型无关。
Mutagenesis. 2004 Jul;19(4):263-8. doi: 10.1093/mutage/geh024.

引用本文的文献

1
Assay to measure CD59 mutations in CHO A(L) cells using flow cytometry.使用流式细胞术检测CHO A(L)细胞中CD59突变的分析方法。
Cytometry A. 2005 Aug;66(2):85-90. doi: 10.1002/cyto.a.20168.
2
Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation.对X射线具有不同突变反应的密切相关的人类淋巴母细胞系中不同的重组能力。
Mol Cell Biol. 1994 Sep;14(9):5850-7. doi: 10.1128/mcb.14.9.5850-5857.1994.
3
Slow clones, reduced clonogenicity, and intraclonal recovery in X-irradiated L5178Y-S cell cultures.
X射线照射的L5178Y-S细胞培养物中克隆生长缓慢、克隆形成能力降低及克隆内恢复情况
Radiat Environ Biophys. 1994;33(2):125-39. doi: 10.1007/BF01219336.