Genotoxicity of gamma-irradiation in L5178Y mouse lymphoma cells.
作者信息
Moore M M, Amtower A, Strauss G H, Doerr C
出版信息
Mutat Res. 1986 Jun;174(2):149-54. doi: 10.1016/0165-7992(86)90107-7.
PMID:3713733
Abstract
The ability of gamma-irradiation to induce gene mutation at the thymidine kinase locus and gross chromosome aberrations in L5178Y TK+/- 3.7.2C mouse lymphoma cells was evaluated. Positive results were obtained for both end-points. The majority of mutants were found to be small-colony mutants which correlated with the induction of gross chromosome aberrations.
摘要
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