Asin F, Scholtmeijer R J
Neth J Surg. 1986 Apr;38(2):56-60.
Xanthogranulomatous pyelonephritis is a rare disease in children. Two young patients of 9 years and 3 months of age are described, with diffuse XPN in a non-functioning left kidney. Nephrectomy was performed in both cases. XPN is a rare variant of chronic, nonspecific pyelonephritis with either diffuse or local segmental involvement of the kidney. Histologically the renal tissue shows a granulomatous inflammatory infiltrate composed of foam cells, plasma cells, lymphocytes and sometimes multinucleated giant cells, abscesses may be present. An accurate preoperative diagnosis is seldom made; in the presence of a non-functioning kidney treatment is nephrectomy.
黄色肉芽肿性肾盂肾炎是儿童罕见疾病。本文描述了两名分别为9岁和3个月大的年轻患者，其左肾无功能，患有弥漫性黄色肉芽肿性肾盂肾炎。两例均行肾切除术。黄色肉芽肿性肾盂肾炎是慢性非特异性肾盂肾炎的一种罕见变体，可累及肾脏的弥漫性或局部节段性区域。组织学上，肾组织表现为肉芽肿性炎性浸润，由泡沫细胞、浆细胞、淋巴细胞组成，有时还有多核巨细胞，可能存在脓肿。术前很少能做出准确诊断；对于无功能肾，治疗方法是肾切除术。
