Di Nola F, Soranzo M L, Bramato C, Salassa B, Andreoni G, Spezia C, Arione R
Minerva Med. 1986 Apr 21;77(17):663-9.
Clinical research was conducted to evaluate the comparative therapeutic efficacy in respiratory pathology of 800 mg X 2 per diem bacampicillin v. 1000 mg X 2 per diem amoxicillin, both orally administered. The results were more or less identical and are interpreted as indicating the better constant absorption of the precursor, hence its higher concentration gradient that produces a higher antibiotic concentration in the lungs.
开展了一项临床研究,以评估每日两次口服800毫克巴卡西林与每日两次口服1000毫克阿莫西林在呼吸道疾病治疗中的相对疗效。结果大致相同,这被解释为表明前体药物的持续吸收更好,因此其更高的浓度梯度能在肺部产生更高的抗生素浓度。