Corinaldesi R, Stanghellini V, Zarabini G E, Raiti C, Rea E, Salgemini R, Giacomoni E, Barbara L
Minerva Med. 1986 Apr 21;77(17):675-7.
The influence of Thyropramide, a recently developed spasmolytic on the gastric emptying times of a solid meal was assessed in 10 healthy subjects aged 23-54. Thyropramide (300 mg per diem for 3 days per os) does not significantly modify gastric emptying time compared to the placebo though a slight average increase in T 1/2 was noted. No side effects were noted during the study. Thyropramide therefore appears to have a spasmolytic effect on the large intestine without in any way influence the stomach either proximally or distally.
在10名年龄在23至54岁的健康受试者中，评估了最近研发的解痉药甲状腺酰胺对固体食物胃排空时间的影响。与安慰剂相比，甲状腺酰胺（每日口服300毫克，共3天）虽使T1/2平均略有增加，但并未显著改变胃排空时间。研究期间未观察到副作用。因此，甲状腺酰胺似乎对大肠有解痉作用，且对胃的近端或远端均无影响。
