Mariammal Muthu, Sahane Nisha, Tiwari Shraeddha
Department of Chemistry, Institute of Chemical Technology, Mumbai, Maharashtra, 400019, India.
Anal Sci. 2023 Aug;39(8):1317-1325. doi: 10.1007/s44211-023-00341-5. Epub 2023 May 4.
Efficient detection and quantification of metal ions in real time and in a cost-effective manner is a critical step in combating the increasing danger of heavy metal contamination of our biosphere. The potential of water-soluble anionic derivative of N-confused tetraphenylporphyrin (WS-NCTPP) has been investigated for quantitative detection of heavy metal ions. The results show that the photophysical properties of WS-NCTPP differ significantly in the presence of four metal ions, namely Hg(II), Zn(II), Co(II) and Cu(II). The variation in the spectral behaviour is driven by the formation of 1:1 complexes with all the four cations with varied degree of complexation. The selectivity of the sensing is studied through interference studies, indicating maximum selectivity for Hg(II) cations. Computational studies of the structural features of the metal complexes with WS-NCTPP help in establishing the geometry and binding interactions between the metal ions and the porphyrin nucleus. The results demonstrate the promising potential of the NCTPP probe which should be utilized for detection of heavy metal ions, especially mercury, in the near future.
以具有成本效益的方式实时高效地检测和定量金属离子，是应对我们生物圈中重金属污染日益增加的危险的关键一步。已对N-杂四苯基卟啉的水溶性阴离子衍生物（WS-NCTPP）定量检测重金属离子的潜力进行了研究。结果表明，在四种金属离子（即Hg(II)、Zn(II)、Co(II)和Cu(II)）存在的情况下，WS-NCTPP的光物理性质有显著差异。光谱行为的变化是由与所有四种阳离子形成1:1配合物驱动的，配合程度各不相同。通过干扰研究对传感的选择性进行了研究，表明对Hg(II)阳离子具有最大选择性。对WS-NCTPP金属配合物结构特征的计算研究有助于确定金属离子与卟啉核之间的几何形状和结合相互作用。结果证明了NCTPP探针的潜在应用前景，在不久的将来应将其用于检测重金属离子，尤其是汞。
