Dorozhenok I Yu
Sechenov First Moscow Medical University (Sechenov University), Moscow, Russia.
Mental Health Research Center, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2023;123(4. Vyp. 2):36-43. doi: 10.17116/jnevro202312304236.
Development of a clinical typology of nosogenic psychosomatic disorders in patients with skin diseases.
The study was carried out in the interclinical psychosomatic department of the Clinical Center and the Clinic of Skin and Venereal Diseases named after. V.A. Rakhmanov Sechenov University in 2007 to 2022. Nine hundred and forty-two patients (253 males, 689 females, average age 37.3±12.4 years) with nosogenic psychosomatic disorders in chronic dermatoses, including ichen planus (=143), psoriasis (=137), atopic dermatitis (=132), acne (=118), rosacea (=115), eczema =10), seborrheic dermatitis (=88), vitiligo (=52), pemphigus (=48), were studied. Index of clinical symptoms (ICS); the Dermatology Quality of Life Index (DQLI); itching severity questionnaire - Behavioral rating scores (BRS); the Hospital Anxiety and Depression Scale (HADS) and statistical methods were used.
In patients with chronic dermatoses, nosogenic psychosomatic disorders were diagnosed according to ICD-10 criteria within adaptation disorders [F43.8] (=465; 49.3%); hypochondriacal disorder [F45.2] (=235; 24.9%); constitutionally determined and acquired (hypochondriac development) personality disorders [F60] (=118; 12.5%); schizotypal disorder [F21] (=65; 6.9%); recurrent depressive disorder [F33] (=59; 6.2%). A typological model of nosogenic disorders in dermatology has been developed: hypochondriacal nosogenies in severe clinical forms of dermatosis (pemphigus, psoriasis, lichen planus, atopic dermatitis, eczema) and dysmorphic nosogenies in objectively mild, but cosmetically significant forms of dermatosis (acne, rosacea, seborrheic dermatitis, vitiligo). When analyzing socio-demographic and psychometric indicators, significant differences were revealed between the selected groups (<0.001). In turn, the selected groups of nosogenic disorders demonstrate significant clinical heterogeneity and include various types of nosogenies that form a unique palette of the nosogenic spectrum in the structure of an extensive psychodermatological continuum. Along with the severity of the skin process, the dominant role in the formation of the clinical picture of nosogeny, including cases of paradoxical dissociation of the quality of life with the severity of dermatosis, amplification and somatization of itching, has a premorbid personality structure and somatoperceptive accentuation of the patient, as well as the presence of a comorbid mental disorder.
The typology of nosogenic psychosomatic disorders in patients with skin diseases requires consideration of both the psychopathological structure of the disorders under discussion and the severity/clinical features of the skin process.
制定皮肤病患者致病因心身障碍的临床分类法。
该研究于2007年至2022年在临床中心的跨临床心身科以及以V.A. 拉赫曼诺夫命名的谢马什克大学皮肤与性病诊所开展。对942例慢性皮肤病致病因心身障碍患者进行了研究(253例男性,689例女性,平均年龄37.3±12.4岁),其中包括扁平苔藓(=143例)、银屑病(=137例)、特应性皮炎(=132例)、痤疮(=118例)、玫瑰痤疮(=115例)、湿疹(=10例)、脂溢性皮炎(=88例)、白癜风(=52例)、天疱疮(=48例)。使用了临床症状指数(ICS);皮肤病生活质量指数(DQLI);瘙痒严重程度问卷 - 行为评分量表(BRS);医院焦虑抑郁量表(HADS)以及统计方法。
根据ICD - 10标准,慢性皮肤病患者的致病因心身障碍诊断如下:适应障碍[F43.8](=465例;49.3%);疑病症[F45.2](=235例;24.9%);体质性和后天性(疑病性发展)人格障碍[F60](=118例;12.5%);分裂样人格障碍[F21](=65例;6.9%);复发性抑郁障碍[F33](=59例;6.2%)。已制定出皮肤病致病因障碍的分类模型:严重临床形式皮肤病(天疱疮、银屑病、扁平苔藓、特应性皮炎、湿疹)中的疑病性致病因和客观上轻度但具有美容意义的皮肤病(痤疮、玫瑰痤疮、脂溢性皮炎、白癜风)中的畸形性致病因。在分析社会人口统计学和心理测量指标时,所选组之间存在显著差异(<0.001)。反过来,所选的致病因障碍组表现出显著的临床异质性,包括各种类型的致病因,这些致病因在广泛的心身皮肤病连续体结构中形成了独特的致病因谱。除了皮肤病变的严重程度外,在致病因临床表现的形成中起主导作用,包括生活质量与皮肤病严重程度的矛盾性分离、瘙痒的放大和躯体化病例,还有病前人格结构和患者的躯体感受性增强以及并存精神障碍的存在。
皮肤病患者致病因心身障碍的分类法需要考虑所讨论障碍的心理病理结构以及皮肤病变的严重程度/临床特征。