Cochran W J, Klish W J, Wong W W, Klein P D
Pediatr Res. 1986 Jun;20(6):561-4. doi: 10.1203/00006450-198606000-00018.
Total body electrical conductivity (TOBEC) has been introduced as a rapid, safe, and noninvasive method suitable for the estimation of fat-free mass. The instrument (EMME or TOBEC) operates on the principle that organisms placed in an electromagnetic field perturb the field to a degree that depends on the amount and volume of distribution of electrolytes present. A study was designed to measure body composition in infants by the TOBEC method and to compare the results with those obtained using the isotope dilution technique. Sixteen infants (age range, 2 days to 9.7 months; weight range, 2 to 8.7 kg) were enrolled. Total body water (TBW) was determined by the isotope dilution technique using H218O. There was a good correlation between the natural logarithm of the TOBEC number and TBW, with a linear correlation coefficient of 0.949. The fat-free body mass of the infants was calculated by TBW (fat-free body mass = /0.082) and by the TOBEC method using the standard previously derived from mature rabbits. TBW measurements by H218O dilution appeared to overestimate fat-free mass which was greater than TBW in five of the 16 infants. Measured by the TOBEC method, fat-free mass ranged from 51 to 91% of total body weight. The TOBEC method is highly suitable for use with human infants and appears to determine body composition as accurately as other available methods.
总体电导率（TOBEC）已作为一种快速、安全且无创的方法被引入，适用于估算去脂体重。该仪器（EMME或TOBEC）的工作原理是，置于电磁场中的生物体对该场的干扰程度取决于存在的电解质的量和分布体积。一项研究旨在通过TOBEC方法测量婴儿的身体成分，并将结果与使用同位素稀释技术获得的结果进行比较。招募了16名婴儿（年龄范围为2天至9.7个月；体重范围为2至8.7千克）。使用H218O通过同位素稀释技术测定总体水（TBW）。TOBEC数值的自然对数与TBW之间存在良好的相关性，线性相关系数为0.949。婴儿的去脂体重通过TBW计算（去脂体重=TBW/0.082），并通过TOBEC方法使用先前从成年兔子得出的标准进行计算。通过H218O稀释测量的TBW似乎高估了去脂体重，在16名婴儿中有5名婴儿的去脂体重超过了TBW。通过TOBEC方法测量，去脂体重占总体重的51%至91%。TOBEC方法非常适合用于人类婴儿，并且似乎能与其他现有方法一样准确地确定身体成分。
