Infectious Diseases Unit, University Hospital Lucus Augusti, Lugo, Spain.
Infectious Diseases Unit, A Coruña University Hospital Complex, A Coruña, Spain.
Eur J Clin Microbiol Infect Dis. 2023 Jul;42(7):907-912. doi: 10.1007/s10096-023-04618-5. Epub 2023 May 5.
Whether cirrhotic patients with Streptococcus bovis bacteremia have an increased risk of colorectal neoplasm is uncertain. A multicentric retrospective cohort study was conducted investigating associations between S. bovis biotype and species, cirrhosis, and colorectal neoplasm. Out of 779 patients with S. bovis bacteremia, 69 (8.7%) had cirrhosis. No differences were found in the prevalence of colorectal neoplasm between cirrhotic and non-cirrhotic patients undergoing colonoscopy. Among cirrhotic patients, prevalence of colorectal neoplasms was higher in S. bovis biotype I (S. gallolyticus) bacteremia (80%) than in S. bovis biotype II (33.3%; p < 0.007). In conclusion, risk of colorectal neoplasm is high among cirrhotic patients with S. gallolyticus bacteremia.
肝硬化合并粪肠球菌菌血症患者发生结直肠肿瘤的风险是否增加尚不确定。本多中心回顾性队列研究旨在调查粪肠球菌生物型和种属、肝硬化和结直肠肿瘤之间的关系。在 779 例粪肠球菌菌血症患者中,69 例(8.7%)合并肝硬化。结肠镜检查的肝硬化和非肝硬化患者中,结直肠肿瘤的患病率无差异。在肝硬化患者中,肠球菌生物型 I(鹑鸡肠球菌)菌血症(80%)的结直肠肿瘤患病率高于生物型 II(33.3%;p<0.007)。结论:肝硬化合并鹑鸡肠球菌菌血症患者发生结直肠肿瘤的风险较高。