Lindros K O, Sipponen P, Pikkarainen P, Turunen U, Salaspuro M
Alcohol Clin Exp Res. 1979 Jan;3(1):78-82. doi: 10.1111/j.1530-0277.1979.tb04773.x.
Rats chronically fed ethanol developed liver injury only if they also received low doses of the alcohol dehydrogenase inhibitor, 4-methylpyrazole, suggesting that the consistency of the influence of ethanol and its metabolism, rather than the level of acetaldehyde or the degree of the metabolic effects, contributes to the pathogenesis of alcoholic liver damage.
