Whiteside James L, Murillo Ashley, Meganathan Karthikeyan, Hohmann Samuel
Department of Obstetrics and Gynecology, University of Cincinnati, College of Medicine, Cincinnati, Ohio.
Division of Biostatistics and Bioinformatics, Department of Environmental & Public Health Sciences, University of Cincinnati, College of Medicine, Cincinnati, Ohio.
Urol Pract. 2021 Nov;8(6):676-681. doi: 10.1097/UPJ.0000000000000255. Epub 2021 Aug 20.
We determined the rate of cystoscopy with hydrodistention (CH) before and after the 2011 American Urological Association (AUA) amended clinical guideline, "Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome."
Clinical encounters with a diagnosis of interstitial cystitis/bladder pain syndrome (IC/BPS) where cystoscopy with and without hydrodistention was performed were identified in the Vizient® Clinical Data Base between January 2009 and February 2020. Demographic and clinical information such as patient age, gender, race, treating physician specialty, insurance type and type of hospital (teaching vs nonteaching) was recorded. Descriptive statistics, Wilcoxon 2-sample test and chi-square test were used to compare variables. An interrupted time series analysis was used to assess the change in CH rate following the June 2011 AUA guideline.
From January 2009 to February 2020, 69,983 encounters were identified to have an IC/BPS diagnosis and to have undergone outpatient cystoscopy, of which 7,502 (10.7%) were CH. Compared to those not undergoing CH, subjects with IC/BPS undergoing CH were younger, predominantly female, Caucasian and had commercial insurance. Before the guideline, across all medical specialties, the base rate of CH was rising from 16.6% at a rate of 0.12% per month. Following guideline release, the CH rate dropped by 6.8%, declining 0.07% per month until February 2020. This pattern was most pronounced in urology relative to all other medical specialties.
The monthly average rate of CH among individuals with IC/BPS undergoing an outpatient CH dropped from nearly 17% before the 2011 AUA guideline to less than 10% in early 2020.
我们确定了2011年美国泌尿外科学会(AUA)修订临床指南《间质性膀胱炎/膀胱疼痛综合征的诊断和治疗》前后膀胱水扩张膀胱镜检查(CH)的发生率。
在Vizient®临床数据库中识别出2009年1月至2020年2月期间诊断为间质性膀胱炎/膀胱疼痛综合征(IC/BPS)且进行了有无膀胱水扩张膀胱镜检查的临床病例。记录患者年龄、性别、种族、主治医生专业、保险类型和医院类型(教学医院与非教学医院)等人口统计学和临床信息。使用描述性统计、Wilcoxon双样本检验和卡方检验来比较变量。采用中断时间序列分析来评估2011年6月AUA指南发布后CH发生率的变化。
2009年1月至2020年2月期间,共识别出69983例诊断为IC/BPS且接受了门诊膀胱镜检查的病例,其中7502例(10.7%)进行了CH。与未进行CH的患者相比,接受CH的IC/BPS患者更年轻,以女性、白种人为主,且拥有商业保险。在该指南发布前,在所有医学专科中,CH的基础发生率以每月0.12%的速度从16.6%上升。指南发布后,CH发生率下降了6.8%,每月下降0.07%,直至2020年2月。相对于所有其他医学专科,这种模式在泌尿外科最为明显。
接受门诊CH的IC/BPS患者中,CH的月平均发生率从2011年AUA指南发布前的近17%降至2020年初的不到10%。