Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Sichuan, 646000, Luzhou, China.
Diagn Pathol. 2023 May 5;18(1):59. doi: 10.1186/s13000-023-01350-8.
Spindle cell tumors, called solitary fibrous tumors (SFTs), are of mesenchymal origin, and can develop in the orbit. As 'intermediate malignancy' tumors, only a small percentage show malignant behavior, such as invasion of surrounding tissue.
A 57-year-old woman presented with a 19-year history of a giant right orbital mass. Orbital computed tomography (CT) revealed an inhomogeneously-enhancing mass compressing and engulfing the eyeball and optic nerve. She underwent lid-sparing orbital exenteration. Microscopic characteristics and immunohistochemistry (IHC) tests were indicative of a benign SFT. No recurrence was observed at the 4-year follow-up.
Early and complete tumor resection is recommended.
梭形细胞肿瘤，称为孤立性纤维瘤（SFT），来源于间叶组织，可发生于眼眶。作为“中度恶性”肿瘤，只有一小部分表现出恶性行为，如侵犯周围组织。
一名 57 岁女性，右侧眼眶巨大肿块病史 19 年。眼眶计算机断层扫描（CT）显示不均匀强化肿块压迫并包绕眼球和视神经。行保留眼睑的眶内容剜除术。显微镜特征和免疫组织化学（IHC）检查提示良性 SFT。4 年随访未见复发。
建议早期、完整地切除肿瘤。
