Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
Department of Histopathology, Sir Gangaram Hospital, New Delhi, India.
J Cancer Res Ther. 2023 Apr;19(Supplement):S0. doi: 10.4103/jcrt.jcrt_282_22.
Ameloblastic carcinoma (AC) is a rare odontogenic malignant epithelial neoplasm of maxillofacial skeleton with a distinct predisposition of the mandible. It can occur in a wide range of age groups, with a sex predilection in males. It can arise either as a de novo lesion or from preexisting ameloblastoma. AC has a high propensity for local recurrence as well as distant metastasis (chiefly lungs), thus requiring an aggressive surgical approach and a strict surveillance. Owing to the rarity of publications describing AC, little is known about this entity in pediatric patients. We report a case of transformation of ameloblastoma into AC in a 10-year-old child.
成釉细胞瘤(AC)是一种罕见的颌面部骨骼牙源性恶性上皮性肿瘤,以下颌多见。它可发生于广泛的年龄组,男性发病倾向更高。其可以作为一个新发病变,也可由已存在的成釉细胞瘤恶变而来。AC 具有较高的局部复发和远处转移(主要是肺部)倾向,因此需要积极的手术治疗和严格的监测。由于描述 AC 的出版物很少,因此对于儿科患者的这种疾病知之甚少。我们报告了一例 10 岁儿童的成釉细胞瘤恶变为 AC 的病例。