Department of Oral and Maxillofacial Pathology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India.
Department of Dentistry, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
J Cancer Res Ther. 2023 Apr;19(Supplement):S422-S425. doi: 10.4103/jcrt.jcrt_1494_22.
Epithelial-myoepithelial carcinoma (EMC), a low-grade malignant neoplasm of glandular origin, most commonly involves major and occasionally minor salivary glands. It is rare in minor salivary glands such as hard and soft palate, buccal mucosa, tongue, and so on, frequently affecting geriatric females. EMC comprises diverse histo-pathologic features of an epithelial, myoepithelial de-lineating biphasic pattern along with clear cells, sometimes oncocytic differentiation. Aberrant histo-pathologic features in EMC need judicious discrimination from alike entities, which facilitates appropriate surgical management. Here, we present an unusual case report of EMC in the left retro-molar trigone region in a 60-year-old male patient, the complete diagnosis of which was based on clinical, radiological, histo-pathological, and immuno-histo-chemical features.
上皮-肌上皮癌（EMC），一种来源于腺体的低级别恶性肿瘤，最常累及大唾液腺，偶尔也会累及小唾液腺。在硬腭和软腭、颊黏膜、舌等小唾液腺中较为罕见，常发生于老年女性。EMC 具有上皮和肌上皮两种成分的形态学特征，形成界限清楚的双相模式，同时伴有透明细胞，有时伴有嗜酸性细胞分化。在 EMC 中，异常的组织病理学特征需要与类似的实体进行谨慎鉴别，这有助于进行适当的手术治疗。在这里，我们报告了一个发生在 60 岁男性患者左侧磨牙后三角区的 EMC 不典型病例，其完整的诊断是基于临床、影像学、组织病理学和免疫组织化学特征。
