Dahl A A
Psychopathology. 1986;19(1-2):68-79. doi: 10.1159/000284431.
The follow-up studies of borderline schizophrenia, the borderline syndrome and borderline personality disorder are examined in the light of modern methodological demands. Few studies reach these standards. The outcome of borderline schizophrenia is variable and close to schizophrenia. Approximately 20% of the cases develop true schizophrenia over time. Grinker's borderline syndrome has also a variable outcome but mostly a poor prognosis. Borderline personality disorder has a variable outcome but better than for schizophrenia. Concomitant major affective disorder is frequently present in borderline personality disorder and influences outcome. The wide range of outcome does not support a single 'natural history' of these disorders. Few predictive factors have been identified. Better studies with the aim of identifying predictive factors are mandatory.
根据现代方法学要求，对边缘型精神分裂症、边缘型综合征和边缘型人格障碍的随访研究进行了审视。很少有研究达到这些标准。边缘型精神分裂症的预后多变，与精神分裂症相近。随着时间推移，约20%的病例会发展为真正的精神分裂症。格林克的边缘型综合征预后也多变，但大多预后不良。边缘型人格障碍预后多变，但比精神分裂症要好。边缘型人格障碍常伴有重度情感障碍，且会影响预后。这些障碍广泛的预后情况并不支持单一的“自然病程”。已确定的预测因素很少。必须开展旨在确定预测因素的更好的研究。
