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Neuronal overexpression of human TDP-43 in causes a range of sensorimotor phenotypes.

作者信息

Koopman Mandy, Güngördü Lale, Seinstra Renée I, Nollen Ellen A A

机构信息

European Research Institute for the Biology of Ageing, University of Groningen, University Medical Centre Groningen, Laboratory of Molecular Neurobiology of Ageing, The Netherlands.

出版信息

MicroPubl Biol. 2023 Apr 19;2023. doi: 10.17912/micropub.biology.000766. eCollection 2023.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84b8/10157381/00100041ea43/25789430-2023-micropub.biology.000766.jpg

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本文引用的文献

1
Neuronal overexpression of hTDP-43 in impairs motor function.
MicroPubl Biol. 2023 Apr 19;2023. doi: 10.17912/micropub.biology.000768. eCollection 2023.
2
Neuronal overexpression of hTDP-43 in mimics the cellular pathology commonly observed in TDP-43 proteinopathies.
MicroPubl Biol. 2023 Apr 19;2023. doi: 10.17912/micropub.biology.000767. eCollection 2023.
3
Neuronal overexpression of hTDP-43 in impairs different neuronally controlled behaviors and decreases fecundity.
MicroPubl Biol. 2023 Apr 19;2023. doi: 10.17912/micropub.biology.000769. eCollection 2023.
4
Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
PLoS Genet. 2019 Dec 13;15(12):e1008526. doi: 10.1371/journal.pgen.1008526. eCollection 2019 Dec.
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Illuminating neural circuits and behaviour in Caenorhabditis elegans with optogenetics.
Philos Trans R Soc Lond B Biol Sci. 2015 Sep 19;370(1677):20140212. doi: 10.1098/rstb.2014.0212.
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The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
PLoS Genet. 2014 Dec 4;10(12):e1004803. doi: 10.1371/journal.pgen.1004803. eCollection 2014 Dec.
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Spiroindolines identify the vesicular acetylcholine transporter as a novel target for insecticide action.
PLoS One. 2012;7(5):e34712. doi: 10.1371/journal.pone.0034712. Epub 2012 May 1.
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Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans.
PLoS One. 2012;7(2):e31321. doi: 10.1371/journal.pone.0031321. Epub 2012 Feb 21.
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Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life span.
J Biol Chem. 2012 Mar 9;287(11):8371-82. doi: 10.1074/jbc.M111.311977. Epub 2012 Jan 9.
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The neural circuits and synaptic mechanisms underlying motor initiation in C. elegans.
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