Cosgrove Lisa, D'Ambrozio Gianna, Herrawi Farahdeba, Freeman Moira, Shaughnessy Allen
Department of Counseling and School Psychology, University of Massachusetts Boston, Boston, MA, United States.
School of Medicine, Tufts University, Boston, MA, United States.
Front Psychiatry. 2023 Apr 21;14:1167910. doi: 10.3389/fpsyt.2023.1167910. eCollection 2023.
The pharmaceutical industry's influence on psychiatric research and practice has been profound and has resulted in exaggerated claims of the effectiveness of psychotropic medications and an under-reporting of harms. After the regulatory approval of fluoxetine, the pharmaceutical industry began promoting (and continues to promote) a chemical imbalance theory of emotional distress. In the last decade, there has been an increased awareness about the limits of this theory and the risks of psychotropic medications. Nonetheless, the medicalization of distress, the sedimented belief in "magic bullets," and the push to "scale up" mental health treatment have contributed to the meteoric rise in the prescription of psychiatric drugs and of polypharmacy. A major premise of this paper is that the conceptual framework of medical nihilism can help researchers and clinicians understand and address the harms incurred by inflated claims of the efficacy of psychotropic medications. We propose that psychiatry, and the mental health field more generally, adopt a model of 'gentle medicine' with regard to both the diagnosis of and treatment for mental health conditions and focus greater attention on the upstream causes of distress.
制药行业对精神病学研究与实践的影响深远,导致了对抗抑郁药物疗效的夸大宣传以及对其危害的报告不足。氟西汀获批上市后,制药行业开始推广(并持续推广)情绪困扰的化学失衡理论。在过去十年里,人们对该理论的局限性以及精神药物的风险有了更多认识。尽管如此,痛苦的医学化、对“神奇药物”根深蒂固的信念以及扩大心理健康治疗规模的推动,导致了精神科药物处方量和联合用药的急剧增加。本文的一个主要前提是,医学虚无主义的概念框架可以帮助研究人员和临床医生理解并应对因夸大精神药物疗效而产生的危害。我们建议,精神病学以及更广泛的心理健康领域,在心理健康状况的诊断和治疗方面采用“温和医学”模式,并更加关注痛苦的上游原因。