Jiravisitkul Paveewan, Thonginnetra Saraiorn, Wongvisavavit Rintra
Department of Pediatrics, Chulabhorn Hospital, Chulabhorn Royal Academy, Bangkok, Thailand.
Princess Srisavangavadhana College of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Front Pediatr. 2023 Apr 19;11:1154814. doi: 10.3389/fped.2023.1154814. eCollection 2023.
This report describes a case of a male infant diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who was prescribed favipiravir therapy. The mother noticed a discoloration of the child's eyes within 18 h of therapy, and the cornea returned to normal color within 5 days of medication cessation. This case report highlights the need for monitoring of favipiravir therapy in children due to the potential side effect of corneal discoloration, which has not yet had its long-term effects identified.
本报告描述了一例被诊断为感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的男婴接受法匹拉韦治疗的病例。母亲在治疗后18小时内注意到孩子眼睛变色,停药后5天角膜恢复正常颜色。本病例报告强调,由于角膜变色这一潜在副作用(其长期影响尚未明确),对儿童进行法匹拉韦治疗时需要进行监测。