Bremond A, Nachury L P, Nicollet B, Quenard N, Martin A
Rev Fr Gynecol Obstet. 1986 Apr;81(4):237-42.
Thanks to recent advances, in-vitro fertilization should alter the clinical indications in cases of sterility due to tubar obstruction. In this article, the authors compare two groups of patients: one group of 109 women treated by means of in-vitro fertilization and another group of 117, treated by microsurgery. In tubar sterility, IVF achieved a 16% pregnancy rate per attempt. In the case of microsurgery, the actuarial rates were calculated (Kaplan Meier method) from a prognostic score. It was found that in the group of women with a "good score", tubar surgery gave results which could be achieved only after 3 or 4 attempts at IVF. On the other hand, in the "poor prognosis" group, IVF was better than microsurgery after a single attempt. Clinical teams should, therefore, reconsider the indications for tubar surgery in the light of the indications for in-vitro fertilization.
由于最近的进展,体外受精应该会改变因输卵管阻塞导致的不育症的临床指征。在本文中,作者比较了两组患者:一组是109名接受体外受精治疗的女性,另一组是117名接受显微外科手术治疗的女性。在输卵管性不育症中,体外受精每次尝试的妊娠率为16%。对于显微外科手术,根据预后评分计算精算率(Kaplan-Meier方法)。结果发现,在“评分良好”的女性组中,输卵管手术的效果只有在体外受精3次或4次尝试后才能达到。另一方面,在“预后不良”组中,单次尝试后体外受精比显微外科手术效果更好。因此,临床团队应该根据体外受精的指征重新考虑输卵管手术的指征。