一项针对接受妇科癌症治疗的中国女性的文化适应性癌症后女性健康计划的可行性和可接受性：一项试点随机对照试验。

Feasibility and acceptability of a culturally-adapted Women's Wellness After Cancer Programme for Chinese women treated for gynaecological cancer: A pilot randomised controlled trial.

作者信息

Chow Ka Ming, Chan Carmen Wing Han, Anderson Debra Jane, Porter-Steele Janine, Leung Alice Wai Yi, Law Bernard Man Hin, McCarthy Alexandra Leigh

机构信息

The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong SAR, China.

Faculty of Health, University of Technology Sydney, Australia.

出版信息

Heliyon. 2023 Apr 18;9(5):e15591. doi: 10.1016/j.heliyon.2023.e15591. eCollection 2023 May.

DOI:10.1016/j.heliyon.2023.e15591

PMID:37153399

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10160754/

Abstract

OBJECTIVE

To assess the feasibility and acceptability of a culturally-adapted Women's Wellness After Cancer Programme (WWACPHK) for improving health-related quality of life, anxiety and depressive symptoms and enhancing self-efficacy in engaging in healthy lifestyles among Chinese women treated for gynaecological cancer.

METHODS

This pilot randomised controlled trial was conducted from May to December 2018. Twenty-six women aged 18 or above who had completed treatment for gynaecological cancer were recruited from a gynaecology outpatient clinic of a public hospital in Hong Kong. They were randomised into intervention (n = 15) or control (n = 11) groups. All data collectors were blinded to the group allocation. Intervention participants were given access to the WWACPHK website and an online discussion forum facilitated by a trained research nurse for 12 weeks, while control participants received standard care. Trial feasibility was assessed by recruitment, consent, and retention rates and website use. Acceptability was explored through semi-structured interviews. Additionally, we trialed the data collection procedure and collected preliminary data on health-related quality of life, anxiety and depressive symptoms, dietary and exercise self-efficacy.

RESULTS

Of the 26 participants (Median age = 53.5 years) randomised, three participants dropped out of the study. Recruitment, consent and retention of participants and website use were satisfactory. No posting was made on the discussion forum. The intervention participants (n = 13) exhibited significantly greater improvement than the controls (n = 10) in perceived self-efficacy in adhering to an exercise routine at post-intervention (Cohen's d effect size(d) = 1.06, 95% confidence interval (CI): 0.18, 1.92) and 12-weeks after completion (d = 1.24, 95% CI: 0.32, 2.13). All participants were satisfied with the intervention.

CONCLUSIONS

The WWACPHK is feasible and acceptable to Chinese women treated for gynaecological cancer and may improve their exercise self-efficacy. A larger-scale study is required to confirm its effects. https://www.isrctn.com identifier: ISRCTN12149499.

摘要

目的

评估一项经过文化调适的癌症后女性健康计划（WWACPHK）对改善接受妇科癌症治疗的中国女性的健康相关生活质量、焦虑和抑郁症状以及增强其采取健康生活方式的自我效能的可行性和可接受性。

方法

这项试点随机对照试验于2018年5月至12月进行。从香港一家公立医院的妇科门诊招募了26名18岁及以上且已完成妇科癌症治疗的女性。她们被随机分为干预组（n = 15）或对照组（n = 11）。所有数据收集者均对分组情况不知情。干预组参与者可访问WWACPHK网站以及由一名经过培训的研究护士主持的在线讨论论坛，为期12周，而对照组参与者接受标准护理。通过招募率、同意率、保留率和网站使用情况评估试验可行性。通过半结构化访谈探索可接受性。此外，我们对数据收集程序进行了试验，并收集了关于健康相关生活质量、焦虑和抑郁症状、饮食和运动自我效能的初步数据。

结果

在随机分组的26名参与者（中位年龄 = 53.5岁）中，有3名参与者退出研究。参与者的招募、同意和保留情况以及网站使用情况均令人满意。讨论论坛上没有发布任何帖子。干预组参与者（n = 13）在干预后（科恩效应量d = 1.06，95%置信区间（CI）：0.18，1.92）以及完成后12周（d = 1.24，95%CI：0.32，2.13）在坚持日常锻炼的自我效能感方面比对照组（n = 10）有显著更大的改善。所有参与者对干预都很满意。