Pettersson G B, Kronogård C O, Rådmark T
Scand J Gastroenterol. 1986 Apr;21(3):305-12. doi: 10.3109/00365528609003080.
Manometry with fluid-filled catheter systems remains an important technique to study esophageal physiology. The influence of mode of infusion, infusion flow rate, and catheter dimensions on the dynamic response and compliance of such systems was studied. To test the dynamic response, a method based on the step response was developed and applied. A pressure impulse--a step function--was produced by burning off a balloon connected to the system. The response to this well-defined impulse recorded by the system--the step response--was analyzed. The highest frequency to which the system responded satisfactorily--the limiting frequency--was calculated and used as a measure of performance. Compliance and inherent postocclusion pressure rise rate were also determined. In low-compliance systems noninfused or infused by hydraulic capillary infusion, limiting frequencies from 8 to 20 Hz were found, and this was much higher than in a high-compliance system infused by a syringe infusion pump. Smaller diameter and increased length of the manometry catheter decreased the limiting frequency. Increased infusion flow rate did not increase the limiting frequency. The step response test seems to be a simple test of dynamic response that can contribute to better understanding of problems involved in pressure recording with fluid-filled catheter systems. Well-performing fluid-filled manometry systems are adequate for esophageal manometry. Inherent postocclusion pressure rise rate is not a measure of dynamic response, and compliance is not the only determinant of performance.
使用充满液体的导管系统进行测压仍然是研究食管生理学的一项重要技术。研究了输注方式、输注流速和导管尺寸对这类系统动态响应和顺应性的影响。为测试动态响应，开发并应用了一种基于阶跃响应的方法。通过烧断连接到系统的气球产生一个压力脉冲——一个阶跃函数。分析系统记录的对这个明确定义的脉冲的响应——阶跃响应。计算系统令人满意响应的最高频率——极限频率——并将其用作性能指标。还测定了顺应性和固有闭塞后压力上升速率。在低顺应性系统中，无论是未输注还是通过液压毛细管输注，极限频率为8至20赫兹，这远高于通过注射器输注泵输注的高顺应性系统。测压导管直径越小、长度增加会降低极限频率。输注流速增加并不会提高极限频率。阶跃响应测试似乎是一种简单的动态响应测试，有助于更好地理解使用充满液体的导管系统进行压力记录所涉及的问题。性能良好的充满液体的测压系统适用于食管测压。固有闭塞后压力上升速率不是动态响应的指标，顺应性也不是性能的唯一决定因素。
