Fang John C, Hilden Kristen, Tuteja Ashok K, Peterson Kathryn A
Department of Gastroenterology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.
Dig Dis Sci. 2004 Oct;49(10):1657-63. doi: 10.1023/b:ddas.0000043382.59539.d3.
Clinical gastrointestinal manometry studies are currently performed with multilumen water-perfused polyvinyl or strain gauge sensor solid-state catheters. A disposable catheter incorporating air-filled balloons has been developed with performance characteristics suitable for esophageal and anorectal manometry studies. Our aim was to compare esophageal and anorectal pressure measurements using this newly developed catheter with measurements obtained using standard solid-state or water-perfused catheters. Measurements of resting LES pressure, esophageal contraction amplitudes, and anorectal rest and squeeze pressures were obtained in 10 healthy volunteers using a solid-state esophageal catheter, a water-perfused anorectal catheter, and air-filled balloon esophageal and anorectal catheters. Correlation coefficient analysis demonstrated that LES pressures, esophageal contraction amplitudes, and anorectal resting and squeeze pressures were not significantly among between the different catheters. We conclude that recently developed air-filled balloon esophageal and anorectal manometry catheters provide very similar measurements of LES, esophageal body, and anorectal sphincter pressures compared to presently used manometry catheters.
目前临床胃肠测压研究使用的是多腔水灌注聚乙烯或应变片传感器固态导管。一种带有充气气球的一次性导管已被研发出来,其性能特征适用于食管和肛门直肠测压研究。我们的目的是将使用这种新研发导管进行的食管和肛门直肠压力测量结果与使用标准固态或水灌注导管获得的测量结果进行比较。使用固态食管导管、水灌注肛门直肠导管以及充气气球食管和肛门直肠导管,对10名健康志愿者的静息LES压力、食管收缩幅度以及肛门直肠静息和挤压压力进行了测量。相关系数分析表明,不同导管之间的LES压力、食管收缩幅度以及肛门直肠静息和挤压压力并无显著差异。我们得出结论,与目前使用的测压导管相比,最近研发的充气气球食管和肛门直肠测压导管在LES、食管体部和肛门直肠括约肌压力测量方面提供了非常相似的结果。