Alikhassi Afsaneh, Skarpathiotakis Mia, Lu Fang-L, Curpen Belinda
Division of Breast Imaging, Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Precision Diagnostics and Therapeutics Program (Laboratory Medicine), Department of Laboratory Medicine and Pathobiology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Breast Dis. 2023;42(1):147-153. doi: 10.3233/BD-220072.
Pseudoangiomatous stromal hyperplasia (PASH) is a benign breast pathology, which most commonly presents incidentally along with other breast pathologies. The etiology and pathogenesis of PASH are still unknown; however, there is some evidence suggesting PASH is hormone dependent. The clinical history, presentation, and imaging appearance of PASH are variable. Clinically, PASH has a wide spectrum of presentations, from being silent to gigantomastia. On imaging, PASH demonstrates various benign to suspicious features. Here we summarize PASH's clinical presentation, histopathology, imaging features, and management.
假血管瘤样间质增生(PASH)是一种乳腺良性病变,最常与其他乳腺病变一起偶然出现。PASH的病因和发病机制尚不清楚;然而,有一些证据表明PASH依赖激素。PASH的临床病史、表现及影像学表现各不相同。临床上,PASH有广泛的表现,从无症状到巨乳症。在影像学上,PASH表现出各种良性至可疑的特征。在此,我们总结PASH的临床表现、组织病理学、影像学特征及处理方法。