Scherrer P, Perret C
Schweiz Med Wochenschr. 1986 Apr 26;116(17):572-4.
Nine patients with nontraumatic rhabdomyolysis underwent preventive treatment for acute renal failure (ARF) (vascular filling, furosemide, dopamine, Na bicarbonate, allopurinol). Four patients developed functional azotemia and 4 others ARF with conserved diuresis and normalization of renal function without substitutive treatment. Only one patient remained oligoanuric and needed hemodialysis for 3 weeks. Comparing these 3 groups it appears that the severity of the renal impairment is due on one hand to the extent of the muscular lysis and on the other to early commencement of preventive treatment.
9例非创伤性横纹肌溶解症患者接受了急性肾衰竭(ARF)的预防性治疗(血管补液、呋塞米、多巴胺、碳酸氢钠、别嘌醇)。4例患者出现功能性氮质血症,另外4例患者发生ARF,尿量保持正常,肾功能在未进行替代治疗的情况下恢复正常。只有1例患者持续少尿,需要进行3周的血液透析。比较这3组患者,似乎肾功能损害的严重程度一方面取决于肌肉溶解的程度,另一方面取决于预防性治疗开始的时间。