School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Org Lett. 2023 May 19;25(19):3508-3511. doi: 10.1021/acs.orglett.3c01092. Epub 2023 May 8.
A yrlodithiin-derived -like cyclophane (), featuring an adaptive geometry with stimuli-responsiveness, was designed and successfully constructed. The dynamic and foldable dithiin subunit endowed the cyclophane with a compressible cavity which can transform from a hex-nut geometry to a nearly rectangular box upon complexing guests with various sizes and shapes. The resulting pseudorotaxane complexes could be dethreaded via electrochemical oxidation. Such an adaptive cavity along with redox-switchable host-guest binding of could enable further applications in complex molecular switches and machines.
一种基于杨立德衍生的类环番（）化合物被设计并成功构建，它具有刺激响应自适应几何形状。动态和可折叠的二噻因亚基赋予环番一个可压缩的空腔，该空腔可以在与各种大小和形状的客体配位时从六螺母形状转变为几乎矩形盒形状。所得的假轮烷配合物可以通过电化学氧化脱螺纹。这种自适应空腔以及的氧化还原开关型主客体结合能力，使它能够在复杂的分子开关和机器中得到进一步的应用。
