Suppr超能文献

皮肤外科手术部位感染的观察性研究。

Surgical site infection in skin surgery-An observational study.

机构信息

Department of Dermatology and Allergy, University Hospital, Ludwig Maximilian University (LMU) Munich, Munich, Germany.

Dr. Philip Frost, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

出版信息

Int Wound J. 2023 Nov;20(9):3514-3522. doi: 10.1111/iwj.14224. Epub 2023 May 8.

Abstract

BACKGROUND

Surgical site infection (SSI) has a significant impact on patients' morbidity and aesthetic results.

OBJECTIVE

To identify risk factors for SSI in dermatologic surgery.

PATIENTS AND METHODS

This prospective, single-centre, observational study was performed between August 2020 and May 2021. Patients that presented for dermatologic surgery were included and monitored for the occurrence of SSI. For statistical analysis, we used a mixed effects logistic regression model.

RESULTS

Overall, 767 patients with 1272 surgical wounds were included in the analysis. The incidence of SSI was 6.1%. Significant risk factors for wound infection were defect size over 10cm (OR 3.64, 95% confidence interval [CI] 1.80-7.35), surgery of cutaneous malignancy (OR 2.96, CI 1.41-6.24), postoperative bleeding (OR 4.63, CI 1.58-13.53), delayed defect closure by local skin flap (OR 2.67, CI 1.13-6.34) and localisation of surgery to the ear (OR 7.75, CI 2.07-28.99). Wound localisation in the lower extremities showed a trend towards significance (OR 3.16, CI 0.90-11.09). Patient-related factors, such as gender, age, diabetes, or immunosuppression, did not show a statistically significant association with postoperative infection.

CONCLUSION

Large defects, surgery of cutaneous malignancy, postoperative bleeding, and delayed flap closure increase the risk for SSI. High-risk locations are the ears and lower extremities.

摘要

背景

手术部位感染(SSI)会显著影响患者的发病率和美观效果。

目的

确定皮肤科手术中 SSI 的危险因素。

患者与方法

本前瞻性、单中心、观察性研究于 2020 年 8 月至 2021 年 5 月进行。纳入接受皮肤科手术的患者,并监测 SSI 的发生情况。采用混合效应逻辑回归模型进行统计分析。

结果

共有 767 例患者的 1272 个手术伤口纳入分析。SSI 的发生率为 6.1%。伤口感染的显著危险因素包括缺损大小超过 10cm(OR 3.64,95%置信区间 [CI] 1.80-7.35)、皮肤恶性肿瘤手术(OR 2.96,CI 1.41-6.24)、术后出血(OR 4.63,CI 1.58-13.53)、局部皮瓣延迟关闭(OR 2.67,CI 1.13-6.34)和手术部位在耳部(OR 7.75,CI 2.07-28.99)。手术部位在下肢有发生 SSI 的趋势(OR 3.16,CI 0.90-11.09)。患者相关因素,如性别、年龄、糖尿病或免疫抑制,与术后感染无统计学显著关联。

结论

大的缺损、皮肤恶性肿瘤手术、术后出血和延迟皮瓣关闭会增加 SSI 的风险。高风险部位是耳朵和下肢。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac98/10588314/46feb20c460e/IWJ-20-3514-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验