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未成熟恒牙牙髓坏死伴冠折露髓的治疗效果:比较再生性牙髓治疗与根尖诱导成形术的回顾性研究。

Treatment outcomes of immature permanent necrotic evaginated teeth: A retrospective study comparing regenerative endodontic procedures with apexification.

机构信息

Department of Paediatric Dentistry, Hubei-MOST KLOS & KLOBM, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

出版信息

Int J Paediatr Dent. 2023 Nov;33(6):595-606. doi: 10.1111/ipd.13079. Epub 2023 May 16.

DOI:10.1111/ipd.13079
PMID:37158340
Abstract

BACKGROUND

Few studies have compared the outcomes of regenerative endodontic procedures (REPs) and calcium hydroxide apexification focusing on necrotic teeth with dens evaginatus.

AIM

To qualitatively and quantitatively compare the treatment outcomes of REPs and calcium hydroxide apexification in teeth with dens evaginatus.

DESIGN

Immature permanent necrotic evaginated teeth treated with REPs or calcium hydroxide apexification for a follow-up period of at least 12 months were included. Tooth success and survival rates were analyzed. Changes in radiographic root length, apical diameter, and radiographic root area (RRA) were quantified. Prognostic factors that might influence RRA were identified via multivariate linear regression analysis.

RESULTS

A total of 112 teeth (50 REP cases and 62 apexification cases) with a median follow-up period of 26.5 months were included. Regenerative endodontic procedures and calcium hydroxide apexification exhibited similar satisfactory success and survival rates (p > .05). Additionally, 88 teeth were quantitatively analyzed. The REP group presented a significantly greater percentage increase in RRA and less decrease in apical diameter than the calcium hydroxide apexification group (p < .05). Teeth treated with REPs and with Stages 7 and 8 of root development showed a better gain in RRA (p < .05).

CONCLUSION

While REP and calcium hydroxide apexification had similar success and survival rates, teeth with REPs showed an increase in RRA, indicating that REP is the preferred choice.

摘要

背景

很少有研究比较再生牙髓治疗(REP)和氢氧化钙根尖诱导成形术在治疗尖牙融合畸形并发牙髓坏死的疗效。

目的

定性和定量比较 REP 和氢氧化钙根尖诱导成形术治疗尖牙融合畸形并发牙髓坏死的疗效。

设计

纳入至少接受 12 个月随访的尖牙融合畸形并发牙髓坏死的未成熟恒牙,分别接受 REP 或氢氧化钙根尖诱导成形术治疗。分析牙齿成功率和存活率。定量评估 X 线片根长、根尖直径和根面积(RRA)的变化。采用多元线性回归分析确定可能影响 RRA 的预后因素。

结果

共纳入 112 颗牙齿(50 例 REP 组和 62 例根尖诱导成形术组),中位随访时间为 26.5 个月。REP 和氢氧化钙根尖诱导成形术的成功率和存活率相似(p>.05)。进一步对 88 颗牙齿进行定量分析,REP 组 RRA 增加百分比显著大于氢氧化钙根尖诱导成形术组,根尖直径减少百分比显著小于氢氧化钙根尖诱导成形术组(p<.05)。REP 治疗的牙齿和根发育处于 7 期和 8 期的牙齿的 RRA 增加更好(p<.05)。

结论

REP 和氢氧化钙根尖诱导成形术的成功率和存活率相似,但 REP 治疗可增加 RRA,因此是更好的选择。

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