Department Health and Human Performance, Plymouth State University, Plymouth, NH, USA -
Department of Kinesiology, University of New Hampshire, Durham, NH, USA -
J Sports Med Phys Fitness. 2023 Aug;63(8):912-920. doi: 10.23736/S0022-4707.23.14860-2. Epub 2023 May 9.
It remains unknown if physical inactivity and excess adiposity increases 24-h central blood pressure and arterial stiffness in young adults. This study examined 24-h central blood pressure and indirect measures of arterial stiffness (e.g., central pulse pressure) in physically inactive young adults with and without excess adiposity.
Body fat and ambulatory 24-h blood pressure were measured in 31 young adults (men: 22±4 years, N.=15; women: 22±5 years, N=16). Multi-frequency bioelectrical impedance measured body fat. Normal adiposity was defined as <20% body fat in men and <32% body fat in women, whereas excess adiposity was defined as ≥20% and ≥32% in men and women, respectively. Ambulatory 24-h central blood pressure was calculated based on brachial blood pressure and volumetric displacement waveforms.
By design, the normal adiposity group had a lower body fat percentage (men: 15.5±4.6%; women: 20.8±2.5%) compared to the physically inactive excess adiposity group (men: 29.8±5.4%; women: 34.3±7.5%). Men and women with excess adiposity group had elevated central blood pressure (central systolic, P<0.05 vs. normal adiposity groups). Central pulse pressure was elevated in the excess adiposity group (men: 45±5 mmHg; women: 41±9 mmHg) compared to normal adiposity groups (men: 36±4 mmHg; women: 32±3 mmHg, P<0.05 for both), while other arterial stiffness (augmentation index and ambulatory arterial stiffness index) measures trended toward significance only in men with excess adiposity.
Physically inactive men and women with excess adiposity have increased 24h central blood pressure and pulse pressure compared to physically inactive young adults with normal adiposity.
目前尚不清楚身体活动不足和肥胖是否会增加年轻人 24 小时中心血压和动脉僵硬度。本研究检测了身体活动不足且伴有或不伴有肥胖的年轻成年人的 24 小时中心血压和动脉僵硬度的间接指标（如中心脉压）。
共纳入 31 名年轻人（男性：22±4 岁，n=15；女性：22±5 岁，n=16），测量其体脂和动态 24 小时血压。多频生物电阻抗法测量体脂。男性体脂正常定义为体脂<20%，女性体脂正常定义为体脂<32%，而男性和女性体脂过多定义为体脂分别≥20%和≥32%。根据肱动脉血压和容积位移波形计算动态 24 小时中心血压。
根据设计，体脂正常组的体脂百分比（男性：15.5±4.6%；女性：20.8±2.5%）明显低于身体活动不足且体脂过多组（男性：29.8±5.4%；女性：34.3±7.5%）。中心收缩压在肥胖组中升高（男性：P<0.05 与体脂正常组）。中心脉压在肥胖组中升高（男性：45±5 mmHg；女性：41±9 mmHg），与体脂正常组相比（男性：36±4 mmHg；女性：32±3 mmHg，均 P<0.05），而在肥胖男性中，其他动脉僵硬度（增强指数和动态动脉僵硬度指数）指标也有升高趋势。
与体脂正常的年轻非体力活动者相比，身体活动不足且肥胖的男性和女性的 24 小时中心血压和脉压更高。
