From the Department of Emergency Medicine, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
McGill University Health Center, Montreal General Hospital, Montreal Children's Hospital, Montreal, Quebec, Canada.
Pediatr Emerg Care. 2024 Apr 1;40(4):319-322. doi: 10.1097/PEC.0000000000002967. Epub 2023 May 10.
The low incidence of blunt cerebrovascular injury (BCVI) reported in pediatric studies (<1%) might be related to an underreporting due to both the absence of current screening guidelines and the use of inadequate imaging techniques. This research is a review of the literature limited to the last 5 years (2017-2022) about the approach and management of BCVI in pediatrics. The strongest predictors for BCVI were the presence of basal skull fracture, cervical spine fracture, intracranial hemorrhage, Glasgow Coma Scale score less than 8, mandible fracture, and injury severity score more than 15. Vertebral artery injuries had the highest associated stroke rate of any injury type at 27.6% (vs 20.1% in carotid injury). The sensitivity of the well-established screening guidelines of BCVI varies when applied to the pediatric population (Utah score - 36%, 17%, Eastern Association for the Surgery of Trauma (EAST) guideline - 17%, and Denver criteria - 2%). A recent metaanalysis of 8 studies comparing early computed tomographic angiogram (CTA) to digital subtraction angiography for BCVI detection in adult trauma patients demonstrated high variability in the sensitivity and specificity of CTA across centers. Overall, CTA was found to have a high specificity but low sensitivity for BCVI. The role of antithrombotic as well as the type and duration of therapy remain controversial. Studies suggest that systemic heparinization and antiplatelet therapy are equally effective.
小儿钝性脑血管损伤(BCVI)的发生率较低(<1%),这可能与缺乏现行的筛查指南以及使用不充分的影像学技术有关,导致漏报。本研究对 2017 年至 2022 年近 5 年的文献进行了回顾,旨在探讨小儿 BCVI 的诊治方法。BCVI 的最强预测因素包括颅底骨折、颈椎骨折、颅内出血、格拉斯哥昏迷量表评分<8、下颌骨骨折和损伤严重程度评分>15。与任何其他损伤类型相比,椎动脉损伤的卒中发生率最高,为 27.6%(颈动脉损伤为 20.1%)。既定的 BCVI 筛查指南应用于儿科人群时,其敏感性存在差异(犹他评分 36%、东部创伤外科学会(EAST)指南 17%、丹佛标准 2%)。最近一项对 8 项成人创伤患者比较早期 CT 血管造影(CTA)与数字减影血管造影(DSA)用于 BCVI 检测的研究进行的荟萃分析显示,CTA 在各中心的敏感性和特异性存在很大差异。总的来说,CTA 对 BCVI 具有较高的特异性,但敏感性较低。抗血栓治疗以及治疗的类型和持续时间仍存在争议。研究表明,全身肝素化和抗血小板治疗同样有效。