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与其他基于凝胶的系统相比,基于比格犬的配方在胃环境中通过控制释放和抗氧化特性更好地保护叶黄素。

A bigel based formulation protects lutein better in the gastric environment with controlled release and antioxidant profile than other gel based systems.

机构信息

Department of Food Engineering and Technology, Institute of Chemical Technology, ICT-IOC Campus, Bhubaneswar 751013, India.

Department of Food Engineering and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400 019, India.

出版信息

Food Chem. 2023 Oct 15;423:136304. doi: 10.1016/j.foodchem.2023.136304. Epub 2023 May 4.

Abstract

Gel based formulations offer an opportunity to fortify bioactives in food. However, a comparative evaluation of gel systems is scantly available. Thus, this study intended to evaluate the impact of various gel formulations (hydrogel, oleogel, emulsion gel, bigels of different compositions) on the delivery and antioxidant activity of lutein. Ethyl cellulose (EC,15 %w/w) and guar-xanthan gum mixture (1:1,1.5 %w/w) was used as oleogelator and hydrogelator, respectively. The microscopic evaluation indicated an oil-based continuous-phase for bigel with 75% oleogel. An increase in oleogel content enhanced textural and rheological properties. An increase in hydrogel composition (25%-75%) of bigel improved the lutein release (70.4%-83.2%). The highest release of lutein was recorded for emulsion gel (84.9%) and bigel with 25% oleogel (83.2%). The antioxidant activity was comparatively lower in gastric medium than simulated intestinal fluid. It could be inferred that the gel matrix significantly affected the lutein release, antioxidant profile, physiochemical and mechanical characteristics.

摘要

凝胶制剂为强化食品中的生物活性物质提供了机会。然而,凝胶系统的比较评估却很少见。因此,本研究旨在评估各种凝胶制剂(水凝胶、油凝胶、乳状凝胶、不同组成的双凝胶)对叶黄素传递和抗氧化活性的影响。乙基纤维素(EC,15%w/w)和瓜尔胶-黄原胶混合物(1:1,1.5%w/w)分别用作油凝胶剂和水凝胶剂。微观评估表明,含有 75%油凝胶的双凝胶具有基于油的连续相。油凝胶含量的增加提高了质构和流变性能。双凝胶中水凝胶组成(25%-75%)的增加提高了叶黄素的释放(70.4%-83.2%)。叶黄素的最大释放是在乳状凝胶(84.9%)和含有 25%油凝胶的双凝胶(83.2%)中记录到的。抗氧化活性在胃介质中比模拟肠液中要低。可以推断,凝胶基质显著影响叶黄素的释放、抗氧化特性、理化和机械特性。

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