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超声诱导的哺乳动物新生脊髓形态学变化。

Ultrasonically induced morphological changes in the mammalian neonatal spinal cord.

作者信息

Borrelli M J, Frizzell L A, Dunn F

出版信息

Ultrasound Med Biol. 1986 Apr;12(4):285-95. doi: 10.1016/0301-5629(86)90338-8.

DOI:10.1016/0301-5629(86)90338-8
PMID:3716004
Abstract

Light and electron microscopy were employed to examine ultrasonically irradiated murine neonate spinal cords. Spinal cord damage was always associated with functional changes, i.e. hind limb paralysis, and was never apparent in initially paralyzed specimens which had recovered function. Damage occurred preferentially at the periphery of the spinal cord and on the ventral side, though the ultrasound was incident on the dorsal side. The distribution of the damage suggests spinal column involvement and nonthermal effects that are enhanced by temperature elevation.

摘要

运用光学显微镜和电子显微镜检查经超声辐照的新生小鼠脊髓。脊髓损伤总是与功能变化相关,即后肢麻痹,而在已恢复功能的初始麻痹标本中从未出现明显损伤。尽管超声是从背侧入射的,但损伤优先发生在脊髓的外周和腹侧。损伤的分布表明脊柱受到累及以及温度升高会增强非热效应。

相似文献

1
Ultrasonically induced morphological changes in the mammalian neonatal spinal cord.超声诱导的哺乳动物新生脊髓形态学变化。
Ultrasound Med Biol. 1986 Apr;12(4):285-95. doi: 10.1016/0301-5629(86)90338-8.
2
Involvement of ultrasonically induced cavitation in the production of hind limb paralysis of the mouse neonate.
J Acoust Soc Am. 1983 Sep;74(3):1062-5. doi: 10.1121/1.389941.
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Exposure levels for ultrasonic cavitation in the mouse neonate.小鼠新生儿超声空化的暴露水平。
Ultrasound Med Biol. 1988;14(8):735-42. doi: 10.1016/0301-5629(88)90029-4.
4
Regrowth of the rostral spinal axons into the caudal ventral roots through a collagen tube implanted into hemisected adult rat spinal cord.通过植入成年大鼠半横断脊髓的胶原管,使延髓脊髓轴突向尾侧腹根再生。
Neurosurgery. 2001 Jul;49(1):143-50; discussion 150-1. doi: 10.1097/00006123-200107000-00022.
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A study of the production of haemorrhagic injury and paraplegia in rat spinal cord by pulsed ultrasound of low megaHertz frequencies in the context of the safety for clinical usage.在临床使用安全性背景下,关于低兆赫兹频率脉冲超声对大鼠脊髓造成出血性损伤和截瘫的研究。
Br J Radiol. 1972 May;45(533):343-53. doi: 10.1259/0007-1285-45-533-343.
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Effects of pulsed ultrasound on the mouse neonate: hind limb paralysis and lung hemorrhage.脉冲超声对新生小鼠的影响:后肢麻痹和肺出血。
J Ultrasound Med. 1998 Jun;17(6):407-8. doi: 10.7863/jum.1998.17.6.407.
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The effect of single doses of radiation on mouse spinal cord.单次辐射剂量对小鼠脊髓的影响。
Int J Radiat Oncol Biol Phys. 1992;22(1):57-63. doi: 10.1016/0360-3016(92)90982-n.
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Hind limb paralysis from electrical shock in three gilts.三只后备母猪因电击导致后肢麻痹。
J Am Vet Med Assoc. 1992 Mar 15;200(6):812-3.
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Rapid functional recovery after spinal cord injury in young rats.幼鼠脊髓损伤后快速的功能恢复
J Neurotrauma. 2005 May;22(5):559-74. doi: 10.1089/neu.2005.22.559.
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Effects of pulsed ultrasound on the mouse neonate: hind limb paralysis and lung hemorrhage.脉冲超声对新生小鼠的影响:后肢麻痹和肺出血。
Ultrasound Med Biol. 1994;20(1):53-63. doi: 10.1016/0301-5629(94)90017-5.

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