Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.
Hospital Santa Rita de Cássia, Departamento de Neurologia e Neurocirurgia, Vitória ES, Brazil.
Arq Neuropsiquiatr. 2023 Apr;81(4):334-339. doi: 10.1055/s-0043-1768157. Epub 2023 May 9.
Despite previous studies indicating a moderate/high incidence of angiography headache (AH), there is still limited data about the risk factors associated with its occurrence.
The present study aimed to assess the associations among demographic, clinical, and technical characteristics of cerebral digital subtraction angiography (DSA) and the occurrence of AH.
Cross-sectional analytical observational study with a sample comprised of individuals with a recommendation for elective DSA. Clinical interviews were conducted to assess the occurrence of AH, using a standardized questionnaire.
Among 114 subjects, the mean age was 52.8 (±13.8) years old, 75.4% (86/114) were women, 29.8% (34/114) had a history of migraines, and 10.5% (12/114) had chronic headaches. The overall frequency of AH was 45.6% (52/114). Of those, 88.4% (46/52) underwent 3D angiography, 7.7% (4/52) underwent aortography, and 1.9% (1/52) underwent both procedures. There was a statistically significant association between AH and previous history of migraine (odds ratio [OR]: 4.9; 95% confidence interval [CI] 1.62-14.7; = 0.005) and 3D angiography (OR 6.62; 95%CI: 2.04-21.5; = 0.002).
3D angiography is strongly associated with the occurrence of AH, which has never been reported before. The association between a previous history of migraine and AH confirms the results of previous studies.
尽管先前的研究表明血管造影头痛（AH）的发生率中等/较高，但与 AH 发生相关的危险因素仍缺乏数据。
本研究旨在评估脑数字减影血管造影（DSA）的人口统计学、临床和技术特征与 AH 发生之间的关联。
横断面分析性观察研究，样本包括接受选择性 DSA 建议的个体。采用标准化问卷进行临床访谈，以评估 AH 的发生情况。
在 114 名受试者中，平均年龄为 52.8（±13.8）岁，75.4%（86/114）为女性，29.8%（34/114）有偏头痛史，10.5%（12/114）有慢性头痛。AH 的总体发生率为 45.6%（52/114）。其中，88.4%（46/52）进行了 3D 血管造影，7.7%（4/52）进行了主动脉造影，1.9%（1/52）同时进行了这两种检查。AH 与偏头痛史（优势比 [OR]：4.9；95%置信区间 [CI]：1.62-14.7； = 0.005）和 3D 血管造影（OR 6.62；95%CI：2.04-21.5； = 0.002）之间存在统计学显著关联。
3D 血管造影与 AH 的发生密切相关，这是以前从未报道过的。偏头痛史与 AH 之间的关联证实了先前研究的结果。
