Department of Computer Science and Engineering, University of Bologna, Bologna, Italy.
Math Biosci Eng. 2023 Feb 9;20(4):7042-7055. doi: 10.3934/mbe.2023304.
During a sanitary crisis, excess mortality measures the number of all-cause deaths, beyond what we would have expected if that crisis had not occurred. The high number of COVID-19 deaths started a debate in Italy with two opposite positions: those convinced that COVID-19 deaths were not by default excess deaths, because many COVID-19 deaths were not correctly registered, with most being attributable to other causes and to the overall crisis conditions; and those who presented the opposite hypothesis. We analyzed the curve of the all-cause excess mortality, during the period of January 5, 2020-October 31, 2022, compared to the curve of the daily confirmed COVID-19 deaths, investigating the association between excess mortality and the recurrence of COVID-19 waves in Italy. We compared the two curves looking for the corresponding highest peaks, and we found that 5 out of the 6 highest peaks (83.3%) of the excess mortality curve have occurred, on average, just a week before the concomitant COVID-19 waves hit their highest peaks of daily deaths (Mean 6.4 days; SD 2.4 days). This temporal correspondence between the moments when the excess mortality peaked and the highest peaks of the COVID-19 deaths, provides further evidence in favor of a positive correlation between COVID-19 deaths and all-cause excess mortality.
在卫生危机期间,超额死亡率衡量的是所有原因导致的死亡人数,超过了如果没有发生这场危机我们预计的死亡人数。大量的 COVID-19 死亡人数引发了意大利的一场辩论,存在两种截然相反的立场:一种观点认为 COVID-19 死亡人数并非默认的超额死亡人数,因为许多 COVID-19 死亡人数没有被正确登记,大多数归因于其他原因和整体危机状况;另一种观点则提出了相反的假设。我们分析了 2020 年 1 月 5 日至 2022 年 10 月 31 日期间所有原因的超额死亡率曲线,与每日确诊的 COVID-19 死亡人数曲线进行了比较,调查了意大利超额死亡率与 COVID-19 浪潮复发之间的关联。我们比较了这两条曲线,寻找相应的最高峰值,发现超额死亡率曲线的 6 个最高峰值中有 5 个(83.3%)平均出现在 COVID-19 死亡人数同时达到每日死亡高峰的前一周(平均值为 6.4 天;标准差为 2.4 天)。这种超额死亡率峰值和 COVID-19 死亡人数峰值出现的时间之间的时间对应关系,进一步证明了 COVID-19 死亡人数与所有原因的超额死亡率之间存在正相关关系。