Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy.
Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.
Med Lav. 2022 Apr 26;113(2):e2022021. doi: 10.23749/mdl.v113i2.13108.
New releases of daily mortality data are available in Italy; the last containing data up to 31 January 2022. This study revises previous estimates of the excess mortality in Italy during the Covid-19 pandemic.
Excess mortality was estimated as the difference between the number of registered deaths and the expected deaths. Expected deaths in March-December 2020, January-December 2021 and January 2022 were estimated separately by sex, through an over-dispersed Poisson regression model using mortality and population data for the period 2011-2019. The models included terms for calendar year, age group, a smooth function of week of the year and the natural logarithm of the population as offset term.
We estimated 99,334 excess deaths (+18.8%) between March and December 2020, 61,808 deaths (+9.5%) in 2021 and 4143 deaths (+6.1%) in January 2022. Over the whole pandemic period, 13,039 excess deaths (+10.2%) were estimated in the age group 25-64 years with most of the excess observed among men [10,025 deaths (+12.6%) among men and 3014 deaths (+6.3%) among women].
Up to 31 January 2022, over 165 thousand excess deaths were estimated in Italy, of these about 8% occurred among the working age population. Despite high vaccination uptake, excess mortality is still observed in recent months.
意大利每日新增死亡数据已更新;最新数据截止至 2022 年 1 月 31 日。本研究重新估算了新冠疫情期间意大利超额死亡率。
超额死亡率定义为登记死亡人数与预期死亡人数之间的差值。2020 年 3 月至 12 月、2021 年 1 月至 12 月和 2022 年 1 月的预期死亡人数分别按性别进行了单独估算,使用 2011 年至 2019 年期间的死亡率和人口数据,通过过离散泊松回归模型进行估算。模型中包含日历年、年龄组、年中周的平滑函数以及人口自然对数作为偏置项的项。
我们估计 2020 年 3 月至 12 月期间有 99334 例超额死亡(+18.8%),2021 年有 61808 例(+9.5%),2022 年 1 月有 4143 例(+6.1%)。在整个大流行期间,25-64 岁年龄组估计有 13039 例超额死亡(+10.2%),其中大部分超额死亡发生在男性中[10025 例男性死亡(+12.6%)和 3014 例女性死亡(+6.3%)]。
截至 2022 年 1 月 31 日,意大利估计有超过 16.5 万例超额死亡,其中约 8%发生在劳动年龄人口中。尽管疫苗接种率很高,但最近几个月仍观察到超额死亡率。