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意大利在新冠疫情期间的超额总死亡率:最新估计表明近几个月仍存在超额死亡率。

Excess total mortality during the Covid-19 pandemic in Italy: updated estimates indicate persistent excess in recent months.

机构信息

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy.

Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.

出版信息

Med Lav. 2022 Apr 26;113(2):e2022021. doi: 10.23749/mdl.v113i2.13108.

DOI:10.23749/mdl.v113i2.13108
PMID:35481574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9073760/
Abstract

BACKGROUND

New releases of daily mortality data are available in Italy; the last containing data up to 31 January 2022. This study revises previous estimates of the excess mortality in Italy during the Covid-19 pandemic.

METHODS

Excess mortality was estimated as the difference between the number of registered deaths and the expected deaths. Expected deaths in March-December 2020, January-December 2021 and January 2022 were estimated separately by sex, through an over-dispersed Poisson regression model using mortality and population data for the period 2011-2019. The models included terms for calendar year, age group, a smooth function of week of the year and the natural logarithm of the population as offset term.

RESULTS

We estimated 99,334 excess deaths (+18.8%) between March and December 2020, 61,808 deaths (+9.5%) in 2021 and 4143 deaths (+6.1%) in January 2022. Over the whole pandemic period, 13,039 excess deaths (+10.2%) were estimated in the age group 25-64 years with most of the excess observed among men [10,025 deaths (+12.6%) among men and 3014 deaths (+6.3%) among women].

CONCLUSIONS

Up to 31 January 2022, over 165 thousand excess deaths were estimated in Italy, of these about 8% occurred among the working age population. Despite high vaccination uptake, excess mortality is still observed in recent months.

摘要

背景

意大利每日新增死亡数据已更新;最新数据截止至 2022 年 1 月 31 日。本研究重新估算了新冠疫情期间意大利超额死亡率。

方法

超额死亡率定义为登记死亡人数与预期死亡人数之间的差值。2020 年 3 月至 12 月、2021 年 1 月至 12 月和 2022 年 1 月的预期死亡人数分别按性别进行了单独估算,使用 2011 年至 2019 年期间的死亡率和人口数据,通过过离散泊松回归模型进行估算。模型中包含日历年、年龄组、年中周的平滑函数以及人口自然对数作为偏置项的项。

结果

我们估计 2020 年 3 月至 12 月期间有 99334 例超额死亡(+18.8%),2021 年有 61808 例(+9.5%),2022 年 1 月有 4143 例(+6.1%)。在整个大流行期间,25-64 岁年龄组估计有 13039 例超额死亡(+10.2%),其中大部分超额死亡发生在男性中[10025 例男性死亡(+12.6%)和 3014 例女性死亡(+6.3%)]。

结论

截至 2022 年 1 月 31 日,意大利估计有超过 16.5 万例超额死亡,其中约 8%发生在劳动年龄人口中。尽管疫苗接种率很高,但最近几个月仍观察到超额死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e55/9073760/e4706a14760c/MDL-113-21-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e55/9073760/2475f48f4598/MDL-113-21-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e55/9073760/e4706a14760c/MDL-113-21-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e55/9073760/2475f48f4598/MDL-113-21-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e55/9073760/e4706a14760c/MDL-113-21-g002.jpg

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