Departement of Clinical Medicine, Public Health, Life and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
PLoS One. 2023 May 10;18(5):e0285464. doi: 10.1371/journal.pone.0285464. eCollection 2023.
Trigeminal electrical stimulation of the dorsal anterior mucosal surface of the tongue has demonstrated its efficacy in a variety of neurological disorders in which anatomical or functional alterations are present. The pathogenesis of such disorders is often linked to altered arousal circuits, and the benefits of tongue stimulation are attributed to the rebalancing of this system. Dental ULFTENS shows efficacy in acting on the muscular, autonomic system and control of the descending pathways that modulate pain. It is administered at the skin level in the area anterior to the tragus and not on the mucosal surface of the tongue. The use of this stimulation technique at the tongue level could have new applications and clinical results if it were able to reduce the activity of arousal circuits.
A new intraoral device allowed electrical stimulation of the dorsal anterior mucosa of the tongue in 32 healthy young women. The effects on HRV were monitored by photoplethysmographic wave (PPG) and compared with a control group. The HRV parameters studied were RMSSD, HF, LF, LF/HF, REC, DET.
The group of stimulated subjects showed a significant change in some of the HRV parameters that was maintained even in the epoch after the end of electrical stimulation. This effect can be considered as a vagal activation and a change of HRV trend. The control group of unstimulated subjects showed an opposite trend. There were no undesirable or annoying effects of stimulation.
Stimulation of the dorsal anterior (trigeminal) mucosal surface of the tongue with ULFTENS applied with an intraoral device was shown to be able to increase HRV.
刺激舌背前黏膜表面的三叉神经电刺激已在多种存在解剖或功能改变的神经疾病中证明了其疗效。这些疾病的发病机制通常与觉醒回路的改变有关，而舌刺激的益处归因于该系统的再平衡。牙科 ULFTENS 在作用于肌肉、自主神经系统和调节疼痛的下行途径的控制方面显示出疗效。它在耳屏前的皮肤区域进行管理，而不在舌黏膜表面进行。如果这种刺激技术能够降低觉醒回路的活动，那么它在舌水平上的应用可能会有新的应用和临床结果。
一种新的口腔内装置允许对 32 名健康年轻女性的舌背前黏膜进行电刺激。通过光体积描记波（PPG）监测 HRV 的影响，并与对照组进行比较。研究的 HRV 参数包括 RMSSD、HF、LF、LF/HF、REC、DET。
刺激组的一些 HRV 参数发生了显著变化，这种变化甚至在电刺激结束后的时段内仍然存在。这种效应可以被认为是迷走神经激活和 HRV 趋势的改变。未受刺激的对照组表现出相反的趋势。刺激没有引起任何不良或烦人的影响。
用口腔内装置施加的 ULFTENS 刺激舌背前（三叉神经）黏膜表面被证明能够增加 HRV。
