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严重急性呼吸综合征冠状病毒 2 感染后磁共振成像阴性的急性炎症性脊髓病。

Magnetic Resonance Imaging-negative Acute Inflammatory Myelopathy following Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

机构信息

Department of Internal Medicine, Japan Self-Defense Forces Central Hospital, Japan.

出版信息

Intern Med. 2023 Aug 1;62(15):2267-2272. doi: 10.2169/internalmedicine.1344-22. Epub 2023 May 10.

Abstract

A 55-year-old woman was admitted to our hospital because of gait disturbance and urinary retention that acutely emerged 1 week after severe acute respiratory syndrome coronavirus 2 infection. Acute inflammatory myelopathy was clinically suspected, based on bilateral lower-limb weakness with an extensor plantar response and an elevated immunoglobulin G level in the cerebrospinal fluid. Whole-spine magnetic resonance imaging findings were normal. The central conduction time was extended, based on somatosensory evoked potentials. Her lower-limb weakness was partially ameliorated with immunosuppressive therapy. Postinfectious myelopathy is a rare neurological complication of coronavirus disease 2019 and can develop with normal radiological findings.

摘要

一位 55 岁女性因严重急性呼吸综合征冠状病毒 2 感染后 1 周突发步态障碍和尿潴留而入院。根据双侧下肢无力伴伸性跖反射和脑脊液免疫球蛋白 G 水平升高,临床疑诊急性炎性脊髓病。全脊柱磁共振成像检查未见异常。体感诱发电位提示中枢传导时间延长。经免疫抑制治疗后,患者下肢无力部分缓解。感染后脊髓病是 2019 冠状病毒病的一种罕见神经系统并发症,可在影像学检查正常的情况下发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87ef/10465296/cc97cbed657b/1349-7235-62-2267-g001.jpg

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