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一项纵向研究中肥胖与动脉粥样硬化风险因素之间的关系

[Relation between obesity and atherogenic risk factors in a longitudinal study].

作者信息

Hunecke I, Reuter W, Sauer I

出版信息

Z Gesamte Inn Med. 1986 Mar 1;41(5):118-24.

PMID:3716501
Abstract

Since 1980 clinical, biochemical and anthropometric examinations have been performed annually on 46 adipose patients (25 males, 18 females) and 53 test persons (35 males, 18 females) at the age of 25 to 40 years. Several of the established parameters (e. g. cholesterol, triglycerides, uric acid, blood pressure among others) in the course of the 5 years within the known normal regions drew towards the adequate limiting value to the pathological. The results of the study clearly show the central role of the overweight for the formation of risk factors. Despite the partly only in a certain tendency recognizable behaviour of individual signs after 5 years from our point of view the longitudinal technique represents itself as a very well suitable method to realize dynamic processes and risk factors of ageing.

摘要

自1980年以来,每年对46名肥胖患者(25名男性,18名女性)和53名25至40岁的测试对象(35名男性,18名女性)进行临床、生化和人体测量检查。在5年的时间里,一些既定参数(如胆固醇、甘油三酯、尿酸、血压等)在已知的正常范围内朝着病理状态的适当极限值靠近。研究结果清楚地表明超重对于危险因素形成的核心作用。尽管从我们的角度来看,5年后个别体征的变化部分仅呈现出一定的趋势,但纵向技术仍是一种非常适合用来认识衰老动态过程和危险因素的方法。

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